Department of Histology and Embryology, Faculty of Medicine, Recep Tayyip Erdogan University, Merkez, Box: 53020, Rize, Turkey.
Department of Anatomy, Faculty of Medicine, Samsun University, Samsun, Turkey.
Environ Sci Pollut Res Int. 2022 Jun;29(26):40123-40130. doi: 10.1007/s11356-021-18325-1. Epub 2022 Feb 3.
Electromagnetic radiation from elecromagnetic field (EMF) sources has been an important health concern for a long time. The vast majority of this exposure is due to the widespread use of mobile phones, an important source of the EMF. The EMF generated by mobile phones may have adverse effects on the various biological structures that regulate the body system and function. In this study, it was aimed to evaluate histopathologically the effects of 900-megahertz (MHz) EMF application in the prenatal period on the development of the ventral cochlear nucleus, which is the first place of hearing in the brainstem, at various time points of the postnatal period in rats. In the study, Sprague-Dawley pregnant rats were divided randomly into two groups as the control group and the EMF group. The rats in the EMF group were exposed to a 900-MHz EMF every day until birth, while no EMF was applied to the rats in the control group. Auditory brainstem responses of both groups were recorded on the postnatal 13th day, the day the hearing starts. Newborn rats were sacrificed by anesthesia on days 7, 10, 15, and 30. Contrary to the control group, structural damage in cochlear nuclear neurons and oligodendrocyte cell structures and increased caspase-3 activity were observed in the postnatal period in the EMF groups. However, no significant difference was observed between the groups in terms of structural damage and caspase-3 activity at different stages of the postnatal period when cochlear nucleus development was observed. According to ABS, there was no significant difference between the average latency of waves in both groups. In conclusion, this study shows that 900-MHz electromagnetic waves propagated from mobile phones during the prenatal period have no harmful effects on the development of the ventral cochlear nucleus of rats.
电磁辐射源的电磁辐射（EMF）长期以来一直是一个重要的健康关注点。这种暴露的绝大多数原因是移动电话的广泛使用，这是 EMF 的一个重要来源。移动电话产生的 EMF 可能对调节身体系统和功能的各种生物结构产生不利影响。在这项研究中，旨在评估 900 兆赫兹（MHz）EMF 在产前应用对大脑脑干中第一个听觉部位腹侧耳蜗核在大鼠出生后不同时间点的发育的组织病理学影响。在研究中，将 Sprague-Dawley 怀孕大鼠随机分为两组，即对照组和 EMF 组。EMF 组的大鼠每天暴露于 900-MHz EMF 中，直到出生，而对照组的大鼠则不接受 EMF。两组大鼠均在出生后第 13 天（听力开始的那一天）记录听觉脑干反应。出生后第 7、10、15 和 30 天，通过麻醉处死新生大鼠。与对照组相比，在 EMF 组的出生后期间观察到耳蜗核神经元和少突胶质细胞结构的结构损伤以及 caspase-3 活性增加。然而，在观察耳蜗核发育的不同阶段时，各组之间在结构损伤和 caspase-3 活性方面没有观察到显著差异。根据 ABS，两组的平均波潜伏期没有显著差异。总之，这项研究表明，产前来自移动电话的 900-MHz 电磁波对大鼠腹侧耳蜗核的发育没有有害影响。
