From the Department of Infectious Disease and Clinical Microbiology, Umraniye Training and Research Hospital, University of Health Science, Istanbul, Turkey.
From the Department of Pulmonology, Sultan Abdulhamid Han Training and Research Hospital, University of Health Science, Istanbul, Turkey.
Ann Saudi Med. 2022 Jan-Feb;42(1):45-51. doi: 10.5144/0256-4947.2022.45. Epub 2022 Feb 3.
Pneumonia is among the most serious infections in the elderly. The evaluation of prognosis and predicting the outcome is essential in managing the treatment of patients with pneumonia.
Evaluate factors that might affect the mortality of elderly patients hospitalized for community-acquired pneumonia (CAP) in two age groups.
Medical record review.
Tertiary care hospital.
The study included CAP patients who were hospitalized during the period from January 2017 and December 2019. The CURB-65 scale was chosen to assess the severity of pneumonia on admission. Multivariate analyses were conducted separately for patients younger than 75 years and 75 years or older.
30-day mortality, factors associated with mortality.
1603 patients with a median age of 74, including 918 women (57%).
The 30-day mortality rate was 6.5%. Patients with carbapenem-resistant gram-negative bacteria had lower survival rates (<.0001). In the multivariate analysis, age, lung cancer, CURB-65, carbapenem resistance, and duration of hospital stay were associated with mortality in patients aged 75 years or older. Lung cancer, malignant disease, carbapenem resistance, duration of hospital stay and procalcitonin level were associated with mortality under the age of 75. Of 640 sputum cultures tested, (42%) was the most common pathogen.
The risk factors that affected mortality differed among patients aged 75 years or older versus younger patients. Our findings are important in determining factors associated with mortality in managing the treatment and follow up of hospitalized CAP patients younger or 75 years of age or older.
Single-center, retrospective.
None.
肺炎是老年人中最严重的感染之一。评估预后和预测结局对于管理肺炎患者的治疗至关重要。
评估可能影响因社区获得性肺炎（CAP）住院的老年患者死亡率的因素，将患者分为两个年龄组。
病历回顾。
三级保健医院。
该研究纳入了 2017 年 1 月至 2019 年 12 月期间因 CAP 住院的患者。入院时使用 CURB-65 评分评估肺炎严重程度。对年龄小于 75 岁和 75 岁或以上的患者分别进行多变量分析。
30 天死亡率、与死亡率相关的因素。
1603 例患者的中位年龄为 74 岁，包括 918 名女性（57%）。
30 天死亡率为 6.5%。耐碳青霉烯类革兰氏阴性菌患者的生存率较低（<0.0001）。在多变量分析中，年龄、肺癌、CURB-65、耐碳青霉烯类和住院时间与 75 岁或以上患者的死亡率相关。肺癌、恶性疾病、耐碳青霉烯类、住院时间和降钙素原水平与 75 岁以下患者的死亡率相关。在 640 份痰培养中，最常见的病原体是（42%）。
年龄在 75 岁或以上的患者与年龄较小的患者相比，影响死亡率的危险因素不同。这些发现对于确定与死亡率相关的因素，从而管理和随访住院的 CAP 患者，无论年龄在 75 岁以下还是以上，都很重要。
单中心、回顾性。
无。
