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一个双种族队列中中年人心血管健康变化的社会人口学决定因素。

Sociodemographic determinants of change in cardiovascular health in middle adulthood in a bi-racial cohort.

作者信息

Lassale Camille, Cené Crystal W, Asselin Anouk, Sims Mario, Jouven Xavier, Gaye Bamba

机构信息

Cardiovascular Epidemiology and Genetics group, Hospital Del Mar Research Institute (IMIM), Barcelona, Spain; CIBER of Pathophysiology of Obesity and Nutrition (CIBEROBN), Instituto de Salud Carlos III, Madrid, Spain.

Department of Medicine, UNC School of Medicine, Chapel Hill, NC, USA.

出版信息

Atherosclerosis. 2022 Apr;346:98-108. doi: 10.1016/j.atherosclerosis.2022.01.006. Epub 2022 Jan 22.

Abstract

BACKGROUND AND AIMS

Cardiovascular health (CVH), as many other aspects of health, is socially patterned. However, little is known about the socioeconomic determinants of following a more or less favourable pattern of CVH change at midlife.

METHODS

We used data on 11,049 participants in the Atherosclerosis Risk in Communities (ARIC) study, a prospective, population-based, bi-racial cohort that included participants aged 44-66 years in 1987-1989, who attended a second visit 6 years later. At both visits, CVH was assessed with the American Heart Association's Life's Simple 7 (LS7) score ranging 0-14, based on 7 metrics: cholesterol, blood glucose, blood pressure, smoking, body mass index, physical activity, and diet. An LS7 score ≥8 was considered ideal, <8 was considered poor. Multivariable logistic regression models were used. In a first sample (N = 4416) of participants who started with a poor CVH, we modelled odds of improvement (Poor-Ideal vs. Poor-Poor). In a second sample (N = 6633) with baseline ideal CVH, we modelled odds of deterioration (Ideal-Poor vs. Ideal-Ideal). The determinants considered were baseline age, sex, race, educational level, income and working status.

RESULTS

The majority (8,347, 75.5%) of participants remained in the same CVH category at both waves: 28.7% poor-poor, and 46.8% ideal-ideal. The remaining 24.5% were evenly split between improving (11.2%) and deteriorating (13.2%). Compared to poor-poor CVH, older participants displayed higher odds of improving to ideal CVH (OR <  = 1.41; 95% CI:1.17, 1.69), whereas Black race (vs White, OR = 0.68; 0.57, 0.80), low education (vs high, OR = 0.65; 0.53, 0.79) and low income (vs high, OR = 0.71; 0.57, 0.87)) were associated with lower odds of improvement. Compared to ideal-ideal CVH, Black participants (OR = 1.59; 1.33, 1.89), with low education (OR = 1.98; 1.64, 2.39), low income (OR = 1.57; 1.30, 1.88), and non-working (vs currently working, OR = 1.27; 1.06, 1.51) had greater odds of deterioration to poor CVH.

CONCLUSIONS

We identified vulnerable groups at higher risk of worsening their CVH over time: Black people, with low income, low education, and who are unemployed. Efforts to reduce income and educational gaps and address structural racism, which shapes the distribution of health-promoting and health-harming resources, are paramount to reduce inequities in CVH.

摘要

背景与目的

心血管健康(CVH)与健康的许多其他方面一样,存在社会模式差异。然而,对于中年时期CVH变化模式或多或少有利的社会经济决定因素,我们知之甚少。

方法

我们使用了社区动脉粥样硬化风险(ARIC)研究中11,049名参与者的数据,这是一项基于人群的前瞻性双种族队列研究,纳入了1987 - 1989年年龄在44 - 66岁的参与者,他们在6年后进行了第二次随访。在两次随访中,根据胆固醇、血糖、血压、吸烟、体重指数、身体活动和饮食这7项指标,使用美国心脏协会的生命简单7项(LS7)评分对CVH进行评估,评分范围为0 - 14分。LS7评分≥8分被认为是理想的,<8分被认为是差的。使用多变量逻辑回归模型。在第一个样本(N = 4416)中,参与者起始的CVH较差,我们对改善的几率(差 - 理想对比差 - 差)进行建模。在第二个样本(N = 6633)中,参与者基线CVH理想,我们对恶化的几率(理想 - 差对比理想 - 理想)进行建模。所考虑的决定因素包括基线年龄、性别、种族、教育水平、收入和工作状态。

结果

大多数(8347名,75.5%)参与者在两次随访中CVH类别保持不变:28.7%为差 - 差,46.8%为理想 - 理想。其余24.5%在改善(11.2%)和恶化(13.2%)之间平均分配。与差 - 差的CVH相比,年龄较大的参与者改善到理想CVH的几率更高(OR <= 1.41;95% CI:1.17,1.69),而黑人种族(与白人相比,OR = 0.68;0.57,0.80)、低教育水平(与高教育水平相比,OR = 0.65;0.53,0.79)和低收入(与高收入相比,OR = 0.71;0.57,0.87)与改善几率较低相关。与理想 - 理想的CVH相比,黑人参与者(OR = 1.59;1.33,1.89)、低教育水平(OR = 1.98;1.64,2.39)、低收入(OR = 1.57;1.30,1.88)以及非在职(与当前在职相比,OR = 1.27;1.06,1.51)恶化到差的CVH的几率更高。

结论

我们确定了随着时间推移CVH恶化风险较高的弱势群体:黑人、低收入、低教育水平以及失业者。努力缩小收入和教育差距并解决结构性种族主义问题(结构性种族主义影响促进健康和损害健康资源的分配)对于减少CVH方面的不平等至关重要。

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