Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada.
Children's Hospital Research Institute of Manitoba, Winnipeg, Manitoba, Canada; Faculty of Health Sciences, College of Medicine, Department of Pediatric and Child Health, University of Manitoba, Winnipeg, Manitoba, Canada.
Can J Diabetes. 2022 Mar;46(2):142-149. doi: 10.1016/j.jcjd.2021.07.005. Epub 2021 Aug 8.
The impacts of stress and disrupted sleep on type 2 diabetes management and related comorbidities in adolescents and youth remain unknown. In this study, we examine sleep in adolescents and youth living with type 2 diabetes and matched controls and its association with stress, glycemic management, albuminuria and hypertension.
A cross-sectional analysis was conducted to assess the relationship between sleep quality (Pittsburgh Sleep Quality Index [PSQI]) and stress (Perceived Stress Scale-14 [PSS-14] and Kessler Psychological Distress Scale [K6]) with metabolic control within a cohort of male and female adolescents and youth (10 to 23 years old) with type 2 diabetes and weight- and ethnicity-matched controls.
One hundred eighty-one adolescents and youth with type 2 diabetes (15.0±2.44 years of age, body mass index z score [BMIz] 1.85±0.60, 62.5% female) and 52 controls (16±2.9 years, BMIz 1.99±0.58, 61.5% female) were included in the investigation. Participants slept for an average of 8.38 hours per night, and 49% of individuals with type 2 diabetes and 46% of controls rated their sleep quality as "poor." No sex differences were seen for sleep scores (p=0.13), but females reported higher stress (p=0.001) and distress (p=0.03). No differences in glycated hemoglobin (p=0.11), BMIz (p=0.28), hypertension (p=0.24) or albuminuria (p=0.79) were seen in individuals reporting good vs poor sleep. Regression analysis showed that poor sleep was associated with higher glycated hemoglobin (p=0.029).
Many adolescents and youth reported poor sleep, which was associated with stress, distress and worse glycemic management. Differences were observed between sexes. The long-term effects of poor sleep and psychological distress warrant further study.
压力和睡眠紊乱对 2 型糖尿病青少年和青年患者的管理以及相关合并症的影响尚不清楚。在这项研究中，我们检查了患有 2 型糖尿病的青少年和青年的睡眠情况，并将其与压力、血糖管理、蛋白尿和高血压相关联。
进行了一项横断面分析，以评估睡眠质量（匹兹堡睡眠质量指数 [PSQI]）和压力（感知压力量表 14 项 [PSS-14] 和凯斯勒心理困扰量表 [K6]）与 2 型糖尿病青少年和青年（10 至 23 岁）患者和体重及种族匹配对照组的代谢控制之间的关系。
共有 181 名患有 2 型糖尿病的青少年和青年（年龄 15.0±2.44 岁，体重指数 z 评分 [BMIz] 1.85±0.60，女性占 62.5%）和 52 名对照者（年龄 16±2.9 岁，BMIz 1.99±0.58，女性占 61.5%）纳入了这项研究。参与者平均每晚睡眠时间为 8.38 小时，49%的 2 型糖尿病患者和 46%的对照组认为自己的睡眠质量“差”。在睡眠评分方面没有发现性别差异（p=0.13），但女性报告的压力（p=0.001）和困扰（p=0.03）更高。糖化血红蛋白（p=0.11）、BMIz（p=0.28）、高血压（p=0.24）或蛋白尿（p=0.79）方面，睡眠质量好的个体与睡眠质量差的个体之间没有差异。回归分析显示，睡眠质量差与糖化血红蛋白升高有关（p=0.029）。
许多青少年和青年报告睡眠质量差，这与压力、困扰和血糖管理更差有关。在性别之间观察到了差异。睡眠质量差和心理困扰的长期影响需要进一步研究。
