Pernet A
Schweiz Med Wochenschr. 1986 Jan 18;116(3):77-82.
A relationship exists between metabolic control and the development of late complications of diabetes. Recently, new strategies of insulin therapy have been developed to normalize blood glucose control, with a view to preventing late complications of diabetes and increasing patients' well-being. Intensified insulin therapy can be performed by multiple insulin injections or by continuous subcutaneous insulin infusion with a pump; regular self-monitoring of blood glucose is mandatory with these types of treatment. Results obtained with both forms of insulin therapy are comparable, although in some cases pump treatment is superior. Intensified insulin therapy is principally aimed at young, motivated and compliant diabetic patients without advanced complications, and at diabetic women before and during pregnancy. The potential risks of intensified insulin therapy are reviewed.
代谢控制与糖尿病晚期并发症的发生之间存在关联。最近，已开发出胰岛素治疗的新策略以使血糖控制正常化，旨在预防糖尿病晚期并发症并提高患者的生活质量。强化胰岛素治疗可通过多次胰岛素注射或使用泵持续皮下胰岛素输注来进行；对于这些类型的治疗，定期自我监测血糖是必不可少的。两种胰岛素治疗形式所获得的结果是可比的，尽管在某些情况下泵治疗更具优势。强化胰岛素治疗主要针对没有晚期并发症的年轻、有积极性且依从性好的糖尿病患者，以及妊娠前和妊娠期间的糖尿病女性。本文综述了强化胰岛素治疗的潜在风险。
