Bai P, Sun J
Cancer Hospital, Chinese Academy of Medical Sciences, Beijing.
Zhonghua Fu Chan Ke Za Zhi. 1995 Oct;30(10):614-7.
To review fifteen cases with primary malignant lymphoma of the female genital tract at Cancer Hospital, Chinese Academy of Medical Sciences from 1980 approximately 1994.
This is a clinical retrospective analysis. There were 7 cases of lymphoma originating in the cervix, 2 in the vagina, 3 in the ovary, 1 in the vulva, endometrium and pelvic cavity respectively. All of the 15 cases were given combination therapy. 3 ovarian lymphoma were treated by surgery and chemotherapy, 2 cervical lymphoma and 1 endometrial lymphoma by surgery, chemotherapy and radiotherapy, 1 pelvic lymphoma by surgery and radiotherapy, others by radiotherapy and chemotherapy.
Two patients are living more than 5 years, 3 patients more than 3 years. 4 patients were followed up for less than 2 years and 6 patients relapsed or died.
The prognosis of ovarian lymphoma is worse than that of other genital sites. Combined and sequential chemotherapy-radiotherapy-chemotherapy is the proper treatment sequence for lymphoma of the cervix, vagina and vulva. Extensive chemotherapy may be an appropriate choice for highly malignant pathological type. Radiation should be given early for large cervical lymphoma.
回顾1980年至1994年中国医学科学院肿瘤医院收治的15例女性生殖道原发性恶性淋巴瘤患者的情况。
本研究为临床回顾性分析。其中淋巴瘤起源于宫颈的有7例，阴道2例，卵巢3例，外阴、子宫内膜及盆腔各1例。15例患者均接受了联合治疗。3例卵巢淋巴瘤采用手术及化疗，2例宫颈淋巴瘤及1例子宫内膜淋巴瘤采用手术、化疗及放疗，1例盆腔淋巴瘤采用手术及放疗，其余采用放疗及化疗。
2例患者存活超过5年，3例超过3年。4例患者随访时间不足2年，6例复发或死亡。
卵巢淋巴瘤的预后较其他生殖道部位差。对于宫颈、阴道及外阴淋巴瘤，联合及序贯化疗-放疗-化疗是合适的治疗顺序。对于高恶性病理类型，广泛化疗可能是合适的选择。对于宫颈巨大淋巴瘤应早期给予放疗。
