Altern Ther Health Med. 2022 Jan;28(1):8-10.
Rice Bran Arabinoxylan Compound (RBAC) is a trusted and proven immunomodulator made from a rice bran extract that has been enzymatically modified with an enzyme complex from the shiitake mushroom.
The study's primary objective was to identify the role of RBAC in supporting cancer therapies.
The author designed an open study.
Participants were 14 patients who are suffering from various type of malignancies.
BRM4 capsules-a commercially available, proprietary RBAC supplement-were administered.
The study measured circulating tumor cells (CTC) and tumor markers-the prostate-specific antigen (PSA) and cancer antigens 125 (CA125) 15-3 (CA15-3), and 27-29 (CA27-29) for the relevant malignancy.
Twelve out of 14 participants completed the protocol, and two participants died during the study. Of the 12 participants completing the study, the CTC levels were reduced in 10, with a statistically significant difference between the testing at baseline and postintervention (P = .0047). The tumor markers of various malignancies decreased for nine out the 12 participants, and one participant experienced remission.
The results suggest that the product can be an effective immunomodulator that can complement conventional cancer treatment.
米糠阿拉伯木聚糖复合物（RBAC）是一种经过酶解修饰的米糠提取物，使用来自香菇的酶复合物进行酶解修饰，是一种可靠且经过验证的免疫调节剂。
该研究的主要目的是确定 RBAC 在支持癌症治疗中的作用。
作者设计了一项开放性研究。
共有 14 名患有各种类型恶性肿瘤的患者参与了该研究。
给予 BRM4 胶囊（一种市售的、专有的 RBAC 补充剂）。
该研究测量了循环肿瘤细胞（CTC）和肿瘤标志物——前列腺特异性抗原（PSA）以及癌症抗原 125（CA125）、15-3（CA15-3）和 27-29（CA27-29），用于相关的恶性肿瘤。
14 名参与者中有 12 名完成了方案，在研究过程中有 2 名参与者死亡。在完成研究的 12 名参与者中，有 10 名的 CTC 水平降低，检测基线和干预后之间存在统计学显著差异（P =.0047）。在 12 名参与者中，有 9 名的各种恶性肿瘤的肿瘤标志物降低，有 1 名参与者获得缓解。
结果表明，该产品可能是一种有效的免疫调节剂，可以补充常规癌症治疗。
