Neuroscience Program, University of Illinois at Urbana-Champaign, United States.
Department of Pathobiology, University of Illinois at Urbana-Champaign, United States.
Maturitas. 2022 Mar;157:62-65. doi: 10.1016/j.maturitas.2021.11.004. Epub 2021 Nov 7.
Phthalates are endocrine-disrupting chemicals that influence endogenous hormones. Few studies have examined the link between phthalates and menopause. A recent secondary analysis revealed that phthalates were associated with self-reported sleep measures in perimenopausal women. However, the associations between phthalate exposure and additional measures of sleep remain unknown. We recruited a population of 27 midlife women (aged 45-54) to study the relationship between phthalate exposure and both subjective and objective measures of sleep. Preliminary results indicate that women with higher phthalate exposure have reduced sleep quality, more frequent sleep disruptions, and more restless sleep compared to women with lower exposure.
邻苯二甲酸酯是一种内分泌干扰化学物质，会影响内源性激素。很少有研究探讨邻苯二甲酸酯与绝经期之间的联系。最近的一项二次分析显示，邻苯二甲酸酯与围绝经期女性的自我报告睡眠指标有关。然而，邻苯二甲酸酯暴露与其他睡眠指标之间的关联尚不清楚。我们招募了 27 名中年女性（年龄 45-54 岁）来研究邻苯二甲酸酯暴露与主观和客观睡眠指标之间的关系。初步结果表明，与暴露水平较低的女性相比，暴露水平较高的女性睡眠质量较差，睡眠中断更频繁，睡眠更不安稳。
