Heteroduplex stabilities in highly repetitive DNA. An hypothesis for the polymorphism of Plasmodium parasite antigenic response.
作者信息
Dodin G
出版信息
FEBS Lett. 1986 Mar 3;197(1-2):5-8. doi: 10.1016/0014-5793(86)80286-1.
PMID:3512307
Abstract
Codon repeats encountered in DNA sequences may formally lead to several double-stranded structures of similar stabilities. This is observed in the highly repetitive sequences of some Plasmodium antigens (S-antigen, CS proteins). It is postulated that gene recombination may occur via various heteroduplex molecules thus leading to antigenic polymorphism of Plasmodium parasites.
摘要
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