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经肛门全直肠系膜切除术与腹腔镜辅助经肛门内拖出术治疗直肠乙状结肠先天性巨结肠的临床疗效比较。

Comparison of clinical outcomes after total transanal and laparoscopic assisted endorectal pull-through in patients with rectosigmoid Hirschsprung disease.

机构信息

Institute of Clinical Medicine, University of Oslo, Oslo, Norway.

Institute of Clinical Medicine, University of Oslo, Oslo, Norway; Department of pediatric surgery, Oslo University Hospital, Oslo, Norway.

出版信息

J Pediatr Surg. 2022 Sep;57(9):69-74. doi: 10.1016/j.jpedsurg.2022.01.011. Epub 2022 Jan 15.

Abstract

BACKGROUND

Total transanal (TERPT) and laparoscopic endorectal pull-through (LERPT) are the most common procedures to treat rectosigmoid Hirschsprung's disease (HD). Since few studies have compared the two methods, we aimed to assess clinical outcomes after TERPT and LERPT in this cross-sectional study.

METHODS AND PATIENTS

All patients with rectosigmoid HD operated with TERPT and LERPT between 2001 and 2018 were eligible. Peri-operative data were registered from patients' records, and bowel function was assessed according to the Krickenbeck classification.

RESULTS

91/97 (94%) patients were included; 46 operated with TERPT and 45 with LERPT. Bowel function was assessed in 80 patients at median seven (4-17) years. There was no difference in functional outcome between the procedures. Unplanned procedures under general anesthesia were frequent; 28% after TERPT and 49% after LERPT (p = 0.04). 11% of TERPT and 29% of LERPT patients got botulinum toxin injections (p = 0.03). In the TERPT group, patients operated in the neonatal period had poorer outcome (78%) than those operated later (24%) (p = 0.005). No difference in operative time, length of hospital stay, and rate of early and late complications was found between the procedures.

CONCLUSION

There was no difference in long-term bowel function in patients with rectosigmoid HD operated with TERPT or LERPT. More LERPT patients had an unplanned procedure under general anesthesia, mostly due to obstructive symptoms.

LEVEL OF EVIDENCE

III.

摘要

背景

全经肛门(TERPT)和腹腔镜经肛门内拖出术(LERPT)是治疗直肠乙状结肠先天性巨结肠(HD)最常用的两种手术方法。由于很少有研究比较这两种方法,我们旨在通过这项横断面研究评估 TERPT 和 LERPT 后的临床结果。

方法和患者

所有于 2001 年至 2018 年期间因直肠乙状结肠 HD 接受 TERPT 和 LERPT 手术的患者均符合条件。围手术期数据来自患者记录,肠功能根据 Krickenbeck 分类进行评估。

结果

共纳入 97 例患者中的 91 例(94%);46 例行 TERPT,45 例行 LERPT。80 例患者在中位时间 7(4-17)年后评估肠功能。两种手术方法的功能结果无差异。在 TERPT 组和 LERPT 组中,分别有 28%和 49%的患者需要在全身麻醉下进行非计划手术(p=0.04)。TERPT 组和 LERPT 组分别有 11%和 29%的患者接受了肉毒杆菌毒素注射(p=0.03)。在 TERPT 组中,新生儿期手术的患者(78%)比后期手术的患者(24%)的结果更差(p=0.005)。两种手术方法在手术时间、住院时间、早期和晚期并发症发生率方面均无差异。

结论

接受 TERPT 或 LERPT 手术的直肠乙状结肠 HD 患者的长期肠功能无差异。更多的 LERPT 患者需要在全身麻醉下进行非计划手术,主要是由于梗阻症状。

证据水平

III 级。

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