Intensive Care Unit, Qinghai Provincial People's Hospital, Xining, Qinghai, China.
Digestive System Department, Qinghai University Affiliated Hospital, Xining, Qinghai, China.
Technol Health Care. 2022;30(S1):225-234. doi: 10.3233/THC-228021.
Patients with unexplained pneumonia appeared in Wuhan, Hubei Province at the end of 2019.
To analyze the clinical data of patients with severe COVID-19.
Medical records of 28 severe patients admitted to the intensive care unit of Wuhan Xinzhou District People's Hospital were collected from January 31 to March 17.
The mortality rate of severe patients in our study was 39.3%. There were statistically significant differences in age, admission systolic blood pressure, lymphocyte count, albumin, total bilirubin, and lactate dehydrogenase between the death group and the survival group (P< 0.05). There were statistically significant differences in APACHE II, CURB-65, SOFA, respiratory frequency, systolic pressure, platelet, procalcitonin, albumin, creatinine, creatine kinase isoenzyme, lactate dehydrogenase, chloride ion, prothrombin time, international normalized ratio, arterial partial pressure of oxygen, and FiO2 at ICU between the death group and the survival group (P< 0.05).
Fever and cough are the main symptoms, which is useful for predicting the prognosis to dynamically measure the APACHE II, CURB-65, SOFA, respiratory frequency, lymphocyte count, platelet, lactate dehydrogenase, and coagulation tests. The drugs that protect the liver and heart may improve the survival rate of patients with severe COVID-19.
不明原因肺炎患者于 2019 年末出现在湖北省武汉市。
分析重症 COVID-19 患者的临床资料。
收集 2020 年 1 月 31 日至 3 月 17 日武汉市新洲区人民医院重症监护病房收治的 28 例重症患者的病历资料。
本研究中重症患者的死亡率为 39.3%。死亡组与存活组在年龄、入院收缩压、淋巴细胞计数、白蛋白、总胆红素、乳酸脱氢酶等方面差异有统计学意义（P<0.05）。APACHE II、CURB-65、SOFA、呼吸频率、收缩压、血小板、降钙素原、白蛋白、肌酐、肌酸激酶同工酶、乳酸脱氢酶、氯离子、凝血酶原时间、国际标准化比值、动脉血氧分压、FiO2 在 ICU 中的差异有统计学意义（P<0.05）。
发热、咳嗽是主要症状，动态测量 APACHE II、CURB-65、SOFA、呼吸频率、淋巴细胞计数、血小板、乳酸脱氢酶和凝血试验有助于预测预后。保护肝脏和心脏的药物可能会提高重症 COVID-19 患者的生存率。
