Medical Research Unit, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Tropical Disease Centre, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia; Department of Microbiology, School of Medicine, Universitas Syiah Kuala, Banda Aceh, Indonesia.
Division of Infectious Diseases, AichiCancer Center Hospital, Chikusa-ku Nagoya, Japan.
J Infect Public Health. 2020 May;13(5):667-673. doi: 10.1016/j.jiph.2020.03.019. Epub 2020 Apr 8.
In early December 2019, an outbreak of coronavirus disease 2019 (COVID-19), caused by a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), occurred in Wuhan City, Hubei Province, China. On January 30, 2020 the World Health Organization declared the outbreak as a Public Health Emergency of International Concern. As of February 14, 2020, 49,053 laboratory-confirmed and 1,381 deaths have been reported globally. Perceived risk of acquiring disease has led many governments to institute a variety of control measures. We conducted a literature review of publicly available information to summarize knowledge about the pathogen and the current epidemic. In this literature review, the causative agent, pathogenesis and immune responses, epidemiology, diagnosis, treatment and management of the disease, control and preventions strategies are all reviewed.
2019 年 12 月初,一种由新型严重急性呼吸系统综合征冠状病毒 2(SARS-CoV-2)引起的 2019 年冠状病毒病(COVID-19)疫情在中国湖北省武汉市爆发。2020 年 1 月 30 日,世界卫生组织宣布该疫情为国际关注的突发公共卫生事件。截至 2020 年 2 月 14 日,全球已报告 49053 例实验室确诊病例和 1381 例死亡病例。对疾病感染风险的认识促使许多国家政府采取了各种控制措施。我们对可公开获取的信息进行了文献回顾,以总结有关病原体和当前疫情的知识。在本次文献回顾中,对病原体的病因、发病机制和免疫反应、流行病学、诊断、治疗和管理、控制和预防策略进行了综述。