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科根-里斯综合征中的黄斑水肿。

Macular edema in Cogan-Reese syndrome.

作者信息

Bouvarel Hugo, Hamard Pascale, Agard Emilie, Billant Jérémy, El Chehab Hussam, Dot Corinne

机构信息

Hôpital d'Instruction des Armées Desgenettes, 108 Boulevard Pinel, 69003, Lyon, France.

Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts, 28 Rue de Charenton, 75012, Paris, France.

出版信息

Am J Ophthalmol Case Rep. 2022 Jan 26;25:101318. doi: 10.1016/j.ajoc.2022.101318. eCollection 2022 Mar.

DOI:10.1016/j.ajoc.2022.101318
PMID:35128161
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8810354/
Abstract

PURPOSE

Iridocorneo-endothelial (ICE) syndrome is known as a rare spectrum causing glaucoma, corneal and iris damages. Retinal complications are uncommon.

OBSERVATIONS

We report the case of a middle-aged woman suffering from a Cogan-Reese Syndrome (CRS) with refractory ocular hypertension (OHT) who presented a cystoid macular edema (CME) during follow up.

CONCLUSIONS AND IMPORTANCE

We suspect the CME to be inflammatory linked to the pathophysiological hypotheses of the CRS. The CME was successfully treated with topical nonsteroidal anti-inflammatory drugs (NSAID). No consensus is available on its duration. A recurrence happened when treatment was stopped, its reintroduction was successful.

摘要

目的

虹膜角膜内皮(ICE)综合征是一种罕见的疾病谱,可导致青光眼、角膜和虹膜损伤。视网膜并发症并不常见。

观察结果

我们报告了一例患有科根-里斯综合征(CRS)并伴有难治性高眼压(OHT)的中年女性病例,该患者在随访期间出现了黄斑囊样水肿(CME)。

结论与意义

我们怀疑CME与CRS的病理生理假说相关的炎症有关。CME通过局部使用非甾体抗炎药(NSAID)成功治愈。关于其持续时间尚无共识。停药后复发,重新用药后成功治愈。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252b/8810354/ee4330d01add/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252b/8810354/cce2d426d074/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252b/8810354/ee4330d01add/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252b/8810354/cce2d426d074/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/252b/8810354/ee4330d01add/gr2.jpg

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Int J Ophthalmol. 2023 Jan 18;16(1):151-155. doi: 10.18240/ijo.2023.01.24. eCollection 2023.

本文引用的文献

1
The iridocorneal endothelial syndrome.虹膜角膜内皮综合征。
Surv Ophthalmol. 2018 Sep-Oct;63(5):665-676. doi: 10.1016/j.survophthal.2018.01.001. Epub 2018 Jan 11.
2
Etiological mechanism of iridocorneal endothelial (ICE) syndrome may involve infection of herpes simplex virus (HSV) and integration of viral genes into human genome.虹膜角膜内皮(ICE)综合征的病因机制可能涉及单纯疱疹病毒(HSV)感染和病毒基因整合到人基因组中。
Med Hypotheses. 2018 Jan;110:50-52. doi: 10.1016/j.mehy.2017.10.023. Epub 2017 Oct 26.
3
Cystoid macular edema associated with iridocorneal endothelial syndrome: a case report.
与虹膜角膜内皮综合征相关的黄斑囊样水肿:一例报告
BMC Ophthalmol. 2016 Sep 1;16(1):155. doi: 10.1186/s12886-016-0333-y.
4
Diagnosis and Management of Iridocorneal Endothelial Syndrome.虹膜角膜内皮综合征的诊断与管理
Biomed Res Int. 2015;2015:763093. doi: 10.1155/2015/763093. Epub 2015 Sep 16.
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[The irido-corneo-endothelial syndrome. The loss of the control of corneal endothelial cell cycle. A review].[虹膜角膜内皮综合征。角膜内皮细胞周期调控的丧失。综述]
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Macular edema and iridocorneal endothelial syndrome: a case report.黄斑水肿与虹膜角膜内皮综合征:一例报告
Cornea. 2005 Mar;24(2):221-3. doi: 10.1097/01.ico.0000138840.37447.b9.
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Long-term surgical outcomes of patients with glaucoma secondary to the iridocorneal endothelial syndrome.虹膜角膜内皮综合征继发青光眼患者的长期手术效果
Ophthalmology. 2001 Oct;108(10):1789-95. doi: 10.1016/s0161-6420(01)00725-4.
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A syndrome of iris nodules, ectopic Descemet's membrane, and unilateral glaucoma.一种伴有虹膜结节、异位后弹力层膜和单侧青光眼的综合征。
Doc Ophthalmol. 1969;26:424-33. doi: 10.1007/BF03186675.
10
On the morphology of cells of posterior cornea in the iridocorneal endothelial syndrome.虹膜角膜内皮综合征中后角膜细胞的形态学研究
Cornea. 1991 May;10(3):233-43. doi: 10.1097/00003226-199105000-00009.