Young D B, Broadbent D A
J Med Microbiol. 1986 Feb;21(1):13-7. doi: 10.1099/00222615-21-1-13.
Lincomycin has a differential effect on exoprotein production by Vibrio cholerae. The production of some proteins, such as cholera toxin and deoxyribonuclease, is stimulated by low concentrations of the drug while production of other proteins, such as protease and alkaline phosphatase, is unaffected. Possible mechanisms of the lincomycin effect are discussed.
林可霉素对霍乱弧菌外蛋白的产生有不同的影响。低浓度的该药物会刺激某些蛋白质的产生,如霍乱毒素和脱氧核糖核酸酶,而其他蛋白质,如蛋白酶和碱性磷酸酶的产生则不受影响。文中讨论了林可霉素作用的可能机制。