Green synthesis of ionic liquid mediated neodymium oxide nanoparticles via abul leaves extract with its biological applications.

Bio-nanoparticles have created a new era of rapid, harmless and nontoxic drugs for various biomedical applications. The nanoparticles (NPs) of rare earth metal oxides attract researcher's attention due to their excellent chemical and physical properties that exhibit potential activity against disease causing pathogens. () abul is a medicinal plant whose leaves are effectively used for the synthesis of neodymium oxide (NdO) NPs. The 1-butyl 3-methyl imidazolium tetrafluoroborate (BMIM BF) ionic liquid is used as a stabilizing agent to get better the morphology and biological properties of NdO NPs. 1-Butene, 4,4-diethoxy-2-methyl is the main compound in abul leaves extract was confirmed by GCMS analysis. The structure of synthesized NdO (without ionic liquid) and NdO-IL (with ionic liquid) NPs is identified by powder X-ray diffraction (PXRD). The vibrations of the different functional groups were investigated by Fourier-transform infrared (FTIR) and Raman spectroscopy. In UV-Vis spectra, the optical absorption was identified to be 210 and 221nm of NdO and NdO-IL samples and the PL spectrum provides blue and green emission peaks at 386 and 554 nm. The X-ray photoelectron spectroscopy (XPS) and DLS spectra illustrate the electronic configuration and particle size of the synthesized NdO-IL NPs. The morphology, surface nature and lattice spacing were analyzed by scanning electron microscopy (SEM) and transmission electron microscopy (TEM). The purity and weight percentage of the compound presented can be identified by the energy-dispersive X-ray spectroscopy (EDX). The biomedical properties such as antibacterial, antioxidant, antidiabetic, anti-inflammatory and anticancer activities were investigated. Finally, the overall biocompatible studies reveal that the ionic liquid assisted NdO NPs can be considered as a potential drug for pharmaceutical and biomedical applications.