Fishman P S
Neurology. 1986 Mar;36(3):389-92. doi: 10.1212/wnl.36.3.389.
Neural transplantation, once deemed impossible, is being studied in many laboratories. Embryonic CNS from a variety of sites can be grafted into an adult host. The foreign cells differentiate and then produce neurotransmitters or neurohormones. Physical connection can be seen between graft and host. Grafting of fetal tissue may be followed by improved function of animals with experimental forms of neurologic disease or physical injury. Grafted segments of peripheral nerve become innervated by central axons that can conduct physiologic impulses. Grafted glial cells can form myelin within the CNS. Therapeutic grafting into the human nervous system may be feasible, but many scientific and ethical questions remain to be addressed.
神经移植,曾经被认为是不可能的,现在正在许多实验室进行研究。来自各种部位的胚胎中枢神经系统可以移植到成年宿主中。外来细胞分化后会产生神经递质或神经激素。可以看到移植物与宿主之间存在物理连接。将胎儿组织移植到患有实验性神经疾病或身体损伤的动物体内后,其功能可能会得到改善。移植的外周神经节段会被能够传导生理冲动的中枢轴突所支配。移植的神经胶质细胞可以在中枢神经系统内形成髓鞘。将其治疗性地移植到人类神经系统中可能是可行的,但许多科学和伦理问题仍有待解决。