Rheumatology Department, Clinical Research Development Center, Imam Reza Hospital, Kermanshah University of Medical Sciences, Kermanshah.
Reumatismo. 2022 Feb 7;73(4). doi: 10.4081/reumatismo.2021.1437.
Neutrophilic myositis (NM) is an inflammatory disorder predominantly characterized by neutrophilic infiltration in the muscles, which is suggested to be an extracutaneous manifestation of neutrophilic dermatosis (ND). NM is a rare disorder which has been occasionally reported in association with hematologic and inflammatory disorders. This case report describes a 45-year-old woman who presented with gradual muscle weakness developed after coronavirus disease 2019 (COVID-19) infection. Electromyography and nerve conduction velocity findings were compatible with inflammatory myopathy and muscle biopsy revealed neutrophilic infiltration. She was successfully treated with intravenous immunoglobulin, prednisolone 1 mg/kg/day and azathioprine 150 mg/day. In conclusion, the COVID-19 infection itself and the drugs used to treat it can cause a number of muscle disorders. Awareness of muscular involvement in COVID-19 infected patients is important for early diagnosis and appropriate treatment.
中性粒细胞性肌炎（NM）是一种炎症性疾病，主要表现为肌肉中的中性粒细胞浸润，被认为是中性粒细胞皮肤病（ND）的一种皮肤外表现。NM 是一种罕见的疾病，偶尔与血液学和炎症性疾病有关。本病例报告描述了一名 45 岁女性，在感染 2019 年冠状病毒病（COVID-19）后出现逐渐进展的肌肉无力。肌电图和神经传导速度检查结果符合炎症性肌病，肌肉活检显示中性粒细胞浸润。她成功地接受了静脉注射免疫球蛋白、泼尼松龙 1mg/kg/天和硫唑嘌呤 150mg/天治疗。总之，COVID-19 感染本身和用于治疗 COVID-19 的药物可引起多种肌肉疾病。了解 COVID-19 感染患者的肌肉受累情况对于早期诊断和适当治疗很重要。
