• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

一项针对减少慢性非癌症疼痛患者处方阿片类药物的门诊干预措施的范围综述。

A scoping review of outpatient interventions to support the reduction of prescription opioid medication for chronic non cancer pain.

机构信息

Hunter Integrated Pain Service, Hunter New England Local Health District, New Lambton, New South Wales, Australia.

School of Nursing and Midwifery, University of Newcastle, Callaghan, New South Wales, Australia.

出版信息

J Clin Nurs. 2022 Dec;31(23-24):3368-3389. doi: 10.1111/jocn.16235. Epub 2022 Feb 7.

DOI:10.1111/jocn.16235
PMID:35132707
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9790561/
Abstract

BACKGROUND

Prescription opioid use is a global health issue. Previous systematic reviews have not identified that any specific intervention supports prescription opioid reduction effectively. In keeping with the nature of a scoping review, this review details an overview of the existing literature on this topic, with quality of evidence being discussed rather than formally analysed.

AIM

This review aimed to examine and describe outpatient interventions that support the reduction of prescription opioid medication for chronic non cancer pain.

ELIGIBILITY CRITERIA

Abstracts were reviewed against the inclusion criteria of outpatient clinical interventions, for the purpose of prescription opioid dose reduction, offered to adults with CNCP.

SOURCES OF EVIDENCE

Following a structured review approach an electronic database search, of Medline, Embase, Cochrane, Cinahl, and Proquest and grey literature was undertaken. Search results were screened by title for relevance.

CHARTING METHODS

Two reviewers adhering to the PRISMA-ScR checklist charted and assessed studies for quality using Critical Appraisal Skills Programme checklist assessment tools. Extracted data were collated and synthesised for presentation as a tabular and narrative review.

RESULTS

From the initial search of 5089 papers, 19 underwent full-text review and quality appraisal. A variety of interventions were described to support reduction in prescription opioid use, however only one study of at least fair quality was able to demonstrate a demonstrated a statistically significant benefit in reducing measured opioid dose compared with a control group. Interventions were implemented in both specialist pain services and in primary care with multidisciplinary and interdisciplinary clinician care. Barriers and facilitators were observed in both settings.

CONCLUSION AND IMPLICATIONS FOR CLINICAL PRACTICE

Further rigorous research needs to be conducted to conclusively answer the question of what outpatient interventions support opioid reduction in chronic non cancer pain. This scoping review is the first step of inquiry in the development of a nursing intervention to support reduction of prescription opioids.

摘要

背景

处方阿片类药物的使用是一个全球性的健康问题。之前的系统评价并未发现任何特定的干预措施能有效地支持减少处方阿片类药物的使用。由于这是一个范围综述,因此本综述详细介绍了关于这一主题的现有文献综述,讨论了证据的质量而不是正式分析。

目的

本综述旨在检查和描述支持减少慢性非癌症疼痛患者处方阿片类药物的门诊干预措施。

纳入标准

对符合门诊临床干预条件的摘要进行了审查,目的是减少慢性非癌症疼痛患者的处方阿片类药物剂量。

证据来源

采用结构化综述方法,对 Medline、Embase、Cochrane、Cinahl 和 Proquest 电子数据库以及灰色文献进行了检索。通过标题筛选搜索结果,以确定其相关性。

图表方法

两名遵循 PRISMA-ScR 清单的审查员使用批判性评价技能计划清单评估工具对研究进行图表记录和质量评估。提取的数据被整理并综合为表格和叙述性综述。

结果

从最初的 5089 篇论文中,有 19 篇经过了全文审查和质量评估。描述了各种干预措施来支持减少处方阿片类药物的使用,但只有一项至少为中等质量的研究能够证明与对照组相比,测量的阿片类药物剂量有统计学意义的减少。干预措施在专科疼痛服务和初级保健中实施,由多学科和跨学科临床医生提供护理。在这两种环境中都观察到了障碍和促进因素。

结论和对临床实践的影响

需要进一步进行严格的研究,才能最终回答什么门诊干预措施支持慢性非癌症疼痛患者减少阿片类药物的使用的问题。本范围综述是开发支持减少处方阿片类药物的护理干预措施的初步研究。

相似文献

1
A scoping review of outpatient interventions to support the reduction of prescription opioid medication for chronic non cancer pain.一项针对减少慢性非癌症疼痛患者处方阿片类药物的门诊干预措施的范围综述。
J Clin Nurs. 2022 Dec;31(23-24):3368-3389. doi: 10.1111/jocn.16235. Epub 2022 Feb 7.
2
Beyond the black stump: rapid reviews of health research issues affecting regional, rural and remote Australia.超越黑木树:影响澳大利亚地区、农村和偏远地区的健康研究问题的快速综述。
Med J Aust. 2020 Dec;213 Suppl 11:S3-S32.e1. doi: 10.5694/mja2.50881.
3
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.在流行地区,服用抗叶酸抗疟药物的人群中,叶酸补充剂与疟疾易感性和严重程度的关系。
Cochrane Database Syst Rev. 2022 Feb 1;2(2022):CD014217. doi: 10.1002/14651858.CD014217.
4
Opioid prescription patterns in Germany and the global opioid epidemic: Systematic review of available evidence.德国阿片类药物处方模式与全球阿片类药物流行:现有证据的系统评价。
PLoS One. 2019 Aug 28;14(8):e0221153. doi: 10.1371/journal.pone.0221153. eCollection 2019.
5
General practitioners' attitudes towards opioids for non-cancer pain: a qualitative systematic review.全科医生对非癌性疼痛使用阿片类药物的态度:一项定性系统评价。
BMJ Open. 2022 Feb 1;12(2):e054945. doi: 10.1136/bmjopen-2021-054945.
6
A Systematic Review of Interventions and Programs Targeting Appropriate Prescribing of Opioids.针对阿片类药物合理处方的干预措施和项目的系统评价。
Pain Physician. 2019 May;22(3):229-240.
7
An Interdisciplinary Approach to Reducing Opioid Prescriptions to Patients with Chronic Pain in a Spinal Cord Injury Center.脊髓损伤中心减少慢性疼痛患者阿片类药物处方的跨学科方法
PM R. 2019 Feb;11(2):135-141. doi: 10.1016/j.pmrj.2018.09.030. Epub 2019 Feb 14.
8
Healthcare provider knowledge, attitudes, beliefs, and practices surrounding the prescription of opioids for chronic non-cancer pain in North America: protocol for a mixed-method systematic review.北美医疗服务提供者在开具阿片类药物治疗慢性非癌性疼痛方面的知识、态度、信念和实践:一项混合方法系统评价的方案。
Syst Rev. 2018 Nov 13;7(1):189. doi: 10.1186/s13643-018-0858-7.
9
Effectiveness of non-opioid interventions to reduce opioid withdrawal symptoms in patients with chronic pain: a systematic review.非阿片类干预措施减少慢性疼痛患者阿片类戒断症状的有效性:系统评价。
Fam Pract. 2022 Mar 24;39(2):295-300. doi: 10.1093/fampra/cmab159.
10
Adverse events associated with medium- and long-term use of opioids for chronic non-cancer pain: an overview of Cochrane Reviews.阿片类药物长期用于慢性非癌性疼痛的相关不良事件:Cochrane系统评价概述
Cochrane Database Syst Rev. 2017 Oct 30;10(10):CD012509. doi: 10.1002/14651858.CD012509.pub2.

引用本文的文献

1
Implementation of pharmaceutical strategies using the PDCA cycle for standardized management of cancer pain medications.运用PDCA循环实施药学策略以规范癌痛药物管理
Support Care Cancer. 2025 Feb 7;33(3):163. doi: 10.1007/s00520-025-09228-9.
2
Pharmacological Strategies to Decrease Long-Term Prescription Opioid Use: A Systematic Review.减少长期处方阿片类药物使用的药理学策略:一项系统评价
J Clin Med. 2024 Dec 19;13(24):7770. doi: 10.3390/jcm13247770.
3
M2 macrophage polarization: a potential target in pain relief.M2 巨噬细胞极化:缓解疼痛的潜在靶点。

本文引用的文献

1
The PRISMA 2020 statement: An updated guideline for reporting systematic reviews.PRISMA 2020 声明:系统评价报告的更新指南。
Int J Surg. 2021 Apr;88:105906. doi: 10.1016/j.ijsu.2021.105906. Epub 2021 Mar 29.
2
Feasibility of patient-focused behavioral interventions to support adults experiencing chronic noncancer pain during opioid tapering: a systematic literature review.以患者为中心的行为干预支持接受阿片类药物递减治疗的慢性非癌痛成人患者的可行性:系统文献回顾。
Transl Behav Med. 2021 Aug 13;11(8):1481-1494. doi: 10.1093/tbm/ibab007.
3
Patient-centered prescription opioid tapering in community outpatients with chronic pain: 2- to 3-year follow-up in a subset of patients.
Front Immunol. 2023 Aug 29;14:1243149. doi: 10.3389/fimmu.2023.1243149. eCollection 2023.
4
Deprescribing Strategies for Opioids and Benzodiazepines with Emphasis on Concurrent Use: A Scoping Review.阿片类药物和苯二氮䓬类药物的减药策略,重点是联合使用:一项范围综述
J Clin Med. 2023 Feb 23;12(5):1788. doi: 10.3390/jcm12051788.
5
Feasibility study of a Behavioural Intervention for Opioid Reduction (BIOR) for patients with chronic non-cancer pain in primary care: a protocol.在初级保健中对慢性非癌性疼痛患者进行行为干预减少阿片类药物使用(BIOR)的可行性研究:方案。
BMJ Open. 2023 Jan 18;13(1):e065646. doi: 10.1136/bmjopen-2022-065646.
以患者为中心的社区慢性疼痛门诊患者处方阿片类药物减量:部分患者的2至3年随访
Pain Rep. 2020 Sep 17;5(5):e851. doi: 10.1097/PR9.0000000000000851. eCollection 2020 Sep-Oct.
4
Integrated Primary Healthcare Opioid Tapering Interventions: A Mixed-Methods Study of Feasibility and Acceptability in Two General Practices in New South Wales, Australia.综合初级医疗保健阿片类药物减量干预措施:澳大利亚新南威尔士州两家普通诊所可行性与可接受性的混合方法研究
Int J Integr Care. 2020 Oct 22;20(4):6. doi: 10.5334/ijic.5426.
5
Deprescribing Opioids in Chronic Non-cancer Pain: Systematic Review of Randomised Trials.在慢性非癌痛中减少阿片类药物的使用:随机试验的系统评价。
Drugs. 2020 Oct;80(15):1563-1576. doi: 10.1007/s40265-020-01368-y.
6
Multidisciplinary care for opioid dose reduction in patients with chronic non-cancer pain: A systematic realist review.多学科团队合作减少慢性非癌痛患者阿片类药物用量:系统的现实主义综述。
PLoS One. 2020 Jul 27;15(7):e0236419. doi: 10.1371/journal.pone.0236419. eCollection 2020.
7
Evaluation of a primary care-based opioid and pain review service: a mixed-methods evaluation in two GP practices in England.基于初级保健的阿片类药物和疼痛审查服务的评估:英格兰两家全科医生实践中的混合方法评估。
Br J Gen Pract. 2020 Jan 30;70(691):e111-e119. doi: 10.3399/bjgp19X707237. Print 2020 Feb.
8
Reducing the use of opioids by patients with chronic pain: an effectiveness study with long-term follow-up.减少慢性疼痛患者使用阿片类药物:一项具有长期随访的有效性研究。
Pain. 2020 Mar;161(3):509-519. doi: 10.1097/j.pain.0000000000001763.
9
Mindfulness-oriented recovery enhancement reduces opioid misuse risk via analgesic and positive psychological mechanisms: A randomized controlled trial.正念导向的康复增强通过镇痛和积极的心理机制降低阿片类药物滥用风险:一项随机对照试验。
J Consult Clin Psychol. 2019 Oct;87(10):927-940. doi: 10.1037/ccp0000390.
10
The role of the opioid system in decision making and cognitive control: A review.阿片类系统在决策和认知控制中的作用:综述。
Cogn Affect Behav Neurosci. 2019 Jun;19(3):435-458. doi: 10.3758/s13415-019-00710-6.