Riebel W, Frantz N, Adelstein D, Spagnuolo P J
Rev Infect Dis. 1986 Jan-Feb;8(1):42-9. doi: 10.1093/clinids/8.1.42.
Ten cases of serious infection due to antibiotic-resistant Corynebacterium JK are reported. Five infections occurred in patients with hematologic malignancy and granulocytopenia, an association previously reported. Five additional nosocomial infections occurred in patients without underlying disease previously reported to be associated with JK. Nine of the 10 infections were nosocomial in origin and were associated with plastic devices that had been inserted into the patients. JK organisms were isolated from a variety of sources from an additional 40 uninfected patients. Although the majority of clinical isolates of Corynebacterium JK were contaminants, our experience suggests that as many as 20% of isolations are associated with serious nosocomial infections. Isolation of Corynebacterium JK--particularly in blood cultures--from patients with indwelling catheters or other devices is highly suggestive of the presence of a serious nosocomial infection.
报告了10例由耐抗生素的JK棒状杆菌引起的严重感染病例。5例感染发生在血液系统恶性肿瘤和粒细胞减少的患者中，这一关联此前已有报道。另外5例医院感染发生在先前未报道与JK相关的无基础疾病患者中。10例感染中有9例起源于医院，且与插入患者体内的塑料装置有关。从另外40名未感染患者的多种来源中分离出了JK菌。尽管JK棒状杆菌的大多数临床分离株是污染物，但我们的经验表明，多达20%的分离株与严重的医院感染有关。从留置导管或其他装置的患者中分离出JK棒状杆菌——尤其是在血培养中——高度提示存在严重的医院感染。
