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低钙血症诱发的 Fahr 综合征发作。

Hypocalcemia-induced seizure with Fahr's syndrome.

机构信息

Service de Médecine Intensive Réanimation, AP-HM, Hôpital Nord, 13015, Marseille, France.

Department of Neuroradiology, APHM La Timone, LIIE, CERIMED, Aix Marseille University, Marseille, France.

出版信息

J Nephrol. 2022 Apr;35(3):1047-1048. doi: 10.1007/s40620-022-01260-w. Epub 2022 Feb 8.

Abstract

INTRODUCTION

Fahr's syndrome is a rare but severe brain complication of hypoparathyroidism and its consequences.

CASE PRESENTATION

A 72-year-old female patient was hospitalized in intensive care unit after two generalized seizures along with a severe hypocalcemia, due to hypoparathyroidism following a thyroidectomy for benign nodules and poor compliance with calcium treatment with treatment due to cognitive disorders. Brain CT showed cortical atrophy and extensive bilateral symmetrical calcifications of the cerebellum, thalami and basal ganglia, typical of Fahr's syndrome.

CONCLUSION

Nephrologists should be aware Fahr's syndrome in patients with hypoparathyroidism, it is associated with an increased risk of seizures. Thus, the control of calcemia in hypoparathyroidism is important, especially in patients with brain calcifications.

摘要

简介

Fahr 综合征是甲状旁腺功能减退症及其后果的一种罕见但严重的脑部并发症。

病例介绍

一名 72 岁女性患者因良性结节甲状腺切除术和认知障碍导致的甲状旁腺功能减退症,以及对钙治疗的依从性差,出现两次全身性癫痫发作和严重低钙血症后,被收入重症监护病房。脑 CT 显示皮质萎缩和广泛双侧对称的小脑、丘脑和基底节钙化,这是 Fahr 综合征的典型表现。

结论

肾病学家应该意识到甲状旁腺功能减退症患者的 Fahr 综合征,它与癫痫发作的风险增加有关。因此,甲状旁腺功能减退症时钙的控制很重要,尤其是在有脑钙化的患者中。

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