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一名17岁癫痫患者患甲状旁腺功能减退伴基底节钙化的罕见病例,该患者同时患有恶性疟原虫疟疾、血小板减少症和贫血。

A Rare Case of Hypoparathyroidism With Basal Ganglia Calcification in a 17-year-old Epileptic Patient Presenting With Falciparum Malaria, Thrombocytopenia and Anemia.

作者信息

Memon Zauha Fawad, Memon Sibgha Fawad, Memon Matia Fawad, Shah Hussain Haider, Hussain Tooba

机构信息

Medicine, Peoples University of Medical and Health Sciences, Nawabshah, Sindh, Pakistan.

Medicine, Dow University of Health Sciences, Karachi, Sindh, Pakistan.

出版信息

Clin Med Insights Case Rep. 2025 Apr 30;18:11795476251332438. doi: 10.1177/11795476251332438. eCollection 2025.

DOI:10.1177/11795476251332438
PMID:40313403
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC12044265/
Abstract

Fahr Syndrome or Strio-Pallido Dentate Calcinosis is a rare neurological syndrome characterized by deposition of calcium in basal ganglia, which usually occurs secondary to other underlying endocrinological disorders like hypo/hyper-parathyroidism. Symptoms vary greatly and may range from psychiatric ones like confusion and hallucination to neurological like Tremors, Rigidity, with seizures being the rarest manifestation. Laboratory tests and brain imaging play a crucial role in establishing the diagnosis, while treatment primarily focuses on managing symptoms. Here, we report a case of a 17-year-old female diagnosed with Fahr's syndrome secondary to hypo-parathyroidism, onset of the disease at such young age coupled with uncommon presentation of fits makes this case rather remarkable.

摘要

法尔综合征或纹状体苍白球齿状核钙化症是一种罕见的神经综合征,其特征是钙在基底神经节沉积,通常继发于其他潜在的内分泌疾病,如甲状旁腺功能减退/亢进。症状差异很大,可能从精神症状如意识模糊和幻觉到神经症状如震颤、僵硬,癫痫发作是最罕见的表现。实验室检查和脑部成像在确立诊断中起关键作用,而治疗主要侧重于症状管理。在此,我们报告一例17岁女性被诊断为继发于甲状旁腺功能减退的法尔综合征,该疾病在如此年轻的年龄发病且伴有不常见的癫痫发作表现,使得该病例相当引人注目。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e9/12044265/46be1238cb66/10.1177_11795476251332438-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e9/12044265/1d114d95f4ae/10.1177_11795476251332438-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e9/12044265/46be1238cb66/10.1177_11795476251332438-fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e9/12044265/1d114d95f4ae/10.1177_11795476251332438-fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77e9/12044265/46be1238cb66/10.1177_11795476251332438-fig2.jpg

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本文引用的文献

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Fahr syndrome and neurological manifestations in hypoparathyroidism patients.法尔综合征与甲状旁腺功能减退患者的神经学表现
Radiol Case Rep. 2024 Jan 13;19(4):1248-1253. doi: 10.1016/j.radcr.2023.12.034. eCollection 2024 Apr.
2
Fahr's syndrome with hypoparathyroidism, thrombocytopenia, and seizure: a rare case report.伴有甲状旁腺功能减退、血小板减少症和癫痫发作的法尔综合征:一例罕见病例报告
Ann Med Surg (Lond). 2023 Jun 28;85(8):4131-4133. doi: 10.1097/MS9.0000000000001032. eCollection 2023 Aug.
3
Hypoparathyroidism and Fahr's Syndrome: A Case Series.
甲状旁腺功能减退症与法尔综合征:病例系列
Cureus. 2023 Jun 16;15(6):e40502. doi: 10.7759/cureus.40502. eCollection 2023 Jun.
4
Hypocalcemia-induced seizure with Fahr's syndrome.低钙血症诱发的 Fahr 综合征发作。
J Nephrol. 2022 Apr;35(3):1047-1048. doi: 10.1007/s40620-022-01260-w. Epub 2022 Feb 8.
5
Thrombocytopenia as a Diagnostic Marker for Malaria in Patients with Acute Febrile Illness.血小板减少症作为急性发热性疾病患者疟疾的诊断标志物
J Trop Med. 2021 Apr 10;2021:5585272. doi: 10.1155/2021/5585272. eCollection 2021.
6
Basal ganglia calcifications (Fahr's syndrome): related conditions and clinical features.基底节钙化(Fahr 综合征):相关疾病及临床特征。
Neurol Sci. 2019 Nov;40(11):2251-2263. doi: 10.1007/s10072-019-03998-x. Epub 2019 Jul 2.
7
Deconstructing Fahr's disease/syndrome of brain calcification in the era of new genes.新基因时代对法尔氏病/脑钙化综合征的剖析
Parkinsonism Relat Disord. 2017 Apr;37:1-10. doi: 10.1016/j.parkreldis.2016.12.024. Epub 2016 Dec 27.
8
Review of Hypoparathyroidism.甲状旁腺功能减退症综述
Front Endocrinol (Lausanne). 2017 Jan 16;7:172. doi: 10.3389/fendo.2016.00172. eCollection 2016.
9
Fahr's Disease or Fahr's Syndrome?法尔氏病还是法尔氏综合征?
Innov Clin Neurosci. 2016 Aug 1;13(7-8):45-6. eCollection 2016 Jul-Aug.
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Neuropsychiatric Profile in Malaria: An Overview.疟疾的神经精神概况:综述
J Clin Diagn Res. 2016 Jul;10(7):OC24-8. doi: 10.7860/JCDR/2016/19035.8169. Epub 2016 Jul 1.