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Fahr 病与甲状旁腺功能减退症——缺失的一环。

Fahr's Disease and Hypoparathyroidism - A Missing Link.

机构信息

Department of Endocrinology, Government Rajaji Hospital and Madurai Medical College, Madurai, Tamil Nadu, India.

出版信息

Neurol India. 2022 May-Jun;70(3):1159-1161. doi: 10.4103/0028-3886.349669.

Abstract

Fahr's disease is an idiopathic basal ganglia calcification with autosomal dominant inheritance. Prior to diagnosing Fahr's disease based on computed tomography (CT) and/or magnetic resonance imaging (MRI) of the brain, one should rule out hypoparathyroidism (HP), and pseudohypoparathyroidism (PHP). Treatments of these conditions are entirely different. HP- and PHP-related hypocalcemia requires calcium, calcitriol, and vitamin D therapy in a long run to avoid recurrent seizures whereas Fahr's disease is treated with an antiepileptic alone.

摘要

特发性基底节钙化伴常染色体显性遗传的 Fahr 病。在基于计算机断层扫描(CT)和/或磁共振成像(MRI)诊断 Fahr 病之前,应排除甲状旁腺功能减退症(HP)和假性甲状旁腺功能减退症(PHP)。这些疾病的治疗方法完全不同。HP 和 PHP 相关的低钙血症需要长期补钙、骨化三醇和维生素 D 治疗,以避免反复癫痫发作,而 Fahr 病仅用抗癫痫药治疗。

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