Park Hong-Kyun, Ko Sang-Bae, Jung Keun-Hwa, Jang Min Uk, Kim Dae-Hyun, Kim Joon-Tae, Choi Jay Chol, Jeong Hye Seon, Kim Chulho, Heo Ji Hoe, Rha Joung-Ho, Kwon Sun U, Kim Jong S, Lee Byung-Chul, Bae Hee-Joon, Yoon Byung-Woo, Hong Keun-Sik
Department of Neurology, Inje University Ilsan Paik Hospital, College of Medicine, Inje University, Goyang, Korea.
Department of Neurology, Seoul National University Hospital, Seoul National University College of Medicine, Seoul, Korea.
J Stroke. 2022 Jan;24(1):166-175. doi: 10.5853/jos.2021.02628. Epub 2022 Jan 31.
Antithrombotic therapy is a cornerstone of acute ischemic stroke (AIS) management and secondary stroke prevention. Since the first version of the Korean Clinical Practice Guideline (CPG) for stroke was issued in 2009, significant progress has been made in antithrombotic therapy for patients with AIS, including dual antiplatelet therapy in acute minor ischemic stroke or high-risk transient ischemic stroke and early oral anticoagulation in AIS with atrial fibrillation. The evidence is widely accepted by stroke experts and has changed clinical practice. Accordingly, the CPG Committee of the Korean Stroke Society (KSS) decided to update the Korean Stroke CPG for antithrombotic therapy for AIS. The writing members of the CPG committee of the KSS reviewed recent evidence, including clinical trials and relevant literature, and revised recommendations. A total of 35 experts were invited from the KSS to reach a consensus on the revised recommendations. The current guideline update aims to assist healthcare providers in making well-informed decisions and improving the quality of acute stroke care. However, the ultimate treatment decision should be made using a holistic approach, considering the specific medical conditions of individual patients.
抗栓治疗是急性缺血性卒中(AIS)管理和二级卒中预防的基石。自2009年发布第一版韩国卒中临床实践指南(CPG)以来,AIS患者的抗栓治疗取得了显著进展,包括急性轻度缺血性卒中或高危短暂性脑缺血发作的双重抗血小板治疗以及伴有心房颤动的AIS患者的早期口服抗凝治疗。这些证据已被卒中专家广泛接受,并改变了临床实践。因此,韩国卒中协会(KSS)的CPG委员会决定更新韩国卒中CPG中关于AIS抗栓治疗的内容。KSS的CPG委员会撰写成员审查了近期证据,包括临床试验和相关文献,并修订了建议。共邀请了35位KSS专家就修订后的建议达成共识。当前的指南更新旨在帮助医疗服务提供者做出明智的决策并提高急性卒中护理质量。然而,最终的治疗决策应采用整体方法,考虑个体患者的具体病情。