Department of Anatomical Sciences, School of Medicine, Zanjan University of Medical Sciences, Zanjan, Iran.
Imam Khomeini Hospital, Tabriz University of Medical Sciences, Tabriz, Iran.
J Med Case Rep. 2022 Feb 8;16(1):63. doi: 10.1186/s13256-021-03245-y.
Beyond the typical respiratory symptoms associated with novel coronavirus, increasing evidence has been reported of the neurological manifestations affecting both the central and peripheral nervous systems.
We observed a 30-year-old Persian woman developing acute motor sensory axonal neuropathy, a variant of Guillain-Barré syndrome that overlaps Miller Fisher syndrome, 30 days after confirmed coronavirus disease-2019 infection. Our case highlight the rare occurrence of Guillain-Barré syndrome overlapping with Miller Fisher during the coronavirus disease-2019 pandemic. These neurologic manifestations may occur because of an aberrant immune response to coronavirus disease-2019.
The early recognition of Guillain-Barré syndrome symptoms is critical, given the associated severe motor disabilities that may seriously limit the quality of life of these patients. We may still have much to learn about the co-occurrence of Guillain-Barré syndrome and Miller Fisher to improve the quality of life of these patients requiring an accurate evaluation by neurologists.
除了与新型冠状病毒相关的典型呼吸道症状外，越来越多的证据表明，新型冠状病毒还会影响中枢和外周神经系统，出现神经系统表现。
我们观察到一名 30 岁的波斯女性在确诊感染 2019 冠状病毒病 30 天后，出现急性运动感觉轴索性神经病，这是吉兰-巴雷综合征的一种变异型，与米勒·费希尔综合征重叠。我们的病例强调了在 2019 冠状病毒病大流行期间，吉兰-巴雷综合征与米勒·费希尔重叠的罕见发生。这些神经系统表现可能是由于对 2019 冠状病毒病的异常免疫反应引起的。
鉴于吉兰-巴雷综合征相关的严重运动障碍可能严重限制这些患者的生活质量，因此早期识别吉兰-巴雷综合征症状至关重要。我们可能仍然需要更多地了解吉兰-巴雷综合征和米勒·费希尔同时发生的情况，以便改善需要神经科医生进行准确评估的这些患者的生活质量。
