Anthony Norah, Duquenne Sebastien, Zemali Nael, Foucher Aurélie, Dupin Nicolas, Bertolotti Antoine
Inserm (French National Institute of Health and Medical Research) CIC1410, University Hospital Center, Saint Pierre, La Réunion, France.
Department of pathology, University Hospital Center, Saint Pierre, La Réunion, France.
Infect Drug Resist. 2022 Feb 1;15:307-310. doi: 10.2147/IDR.S342027. eCollection 2022.
Erythema nodosum (EN) is a dermatological manifestation, the common etiologies of which are already widely described. Here, we report the case of a patient who presented an EN, where the etiology was found to be a rare diagnosis: syphilis, a sexually transmitted infection with various clinical presentations. A 42-year-old female patient without any medical condition presented with a clinical picture associating a maculopapular rash at first, and later on a well-defined hypodermic lesion, clinically suggestive of an EN, on the right forearm. The etiologic workup ruled out sarcoidosis, which was the first suspected diagnosis. Positive VDRL-TPHA and recovery within 15 days after benzathine benzylpenicillin administration allowed the diagnosis of syphilis to be made on the EN. EN is a rare manifestation of syphilis that should be kept in mind in these times of strong recrudescence of the disease among men who have sex with men in mainland France but also among heterosexuals in Reunion Island.
结节性红斑（EN）是一种皮肤表现，其常见病因已被广泛描述。在此，我们报告一例出现结节性红斑的患者，其病因被发现是一种罕见诊断：梅毒，一种具有多种临床表现的性传播感染。一名42岁无任何基础疾病的女性患者，最初表现为斑丘疹皮疹，随后右前臂出现边界清晰的皮下病变，临床提示为结节性红斑。病因检查排除了最初怀疑的诊断——结节病。VDRL - TPHA阳性以及苄星青霉素给药后15天内康复，使得在该结节性红斑病例中诊断出梅毒。结节性红斑是梅毒的一种罕见表现，在法国大陆男男性行为者中以及留尼汪岛异性恋者中该疾病强烈复发的当下，应予以重视。
