Department of Environmental Health, Faculty of Public Health, Universitas Indonesia, Depok, Jawa Barat, 16424, Indonesia.
Alumni of Master Program of Public Health, Universitas Indonesia, Depok, Jawa Barat, 16424, Indonesia.
F1000Res. 2021 Mar 10;10:200. doi: 10.12688/f1000research.46883.2. eCollection 2021.
: The application of insecticides for malaria vector control has led to a global problem, which is the current trend of increased resistance against these chemicals. This study aimed to review the insecticide resistance status was previously determined in Asia and how to implement the necessary interventions. Moreover, the implications of resistance in malaria vector control in this region were studied. : This systematic review was conducted using a predefined protocol based on PRISMA-retrieved articles from four science databases, namely ProQuest, Science Direct, EBSCO, and PubMed in the last ten years (2009 to 2019). The searching process utilized four main combinations of the following keywords: malaria, vector control, insecticide, and Asia. In ProQuest, malaria control, as well as an insecticide, were used as keywords. The following criteria were included in the filter, namely full text, the source of each article, scholarly journal, Asia, and publication date as in the last ten years. : There were 1408 articles retrieved during the initial search (ProQuest=722, Science Direct=267, EBSCO=50, PubMed=285, and Scopus=84). During the screening, 27 articles were excluded because of duplication, 1361 based on title and abstract incompatibility with the inclusion criteria, and 20 due to content differences. In the final screening process, 15 articles were chosen to be analyzed. From the 15 articles, it is known that there was organochlorine (DDT), organophosphate (malathion), and pyrethroids resistance in several Anopheles species with a less than 80% mortality rate. : This review found multiple resistance in several Anopheles includes resistance to pyrethroid. The reports of pyrethroid resistance were quite challenging because it is considered effective in the malaria vector control. Several countries in Asia are implementing an insecticide resistance management (IRM) strategy against malaria vectors following the Global Plan for IRM.
: 杀虫剂在疟疾媒介控制中的应用导致了一个全球性问题，即目前这些化学物质的抗药性呈上升趋势。本研究旨在回顾亚洲以前确定的杀虫剂抗性状况以及如何实施必要的干预措施。此外，还研究了该地区疟疾媒介控制中抗药性的影响。: 本系统评价是根据 PRISMA 从四个科学数据库（ProQuest、Science Direct、EBSCO 和 PubMed）检索到的文章，使用预先设定的方案进行的，检索时间为过去十年（2009 年至 2019 年）。检索过程使用了以下四个主要关键词的组合：疟疾、媒介控制、杀虫剂和亚洲。在 ProQuest 中，疟疾控制以及杀虫剂被用作关键词。筛选中包括以下标准：全文、文章来源、学术期刊、亚洲和过去十年内的出版日期。: 初步搜索共检索到 1408 篇文章（ProQuest=722，Science Direct=267，EBSCO=50，PubMed=285，Scopus=84）。在筛选过程中，由于重复、27 篇文章因标题和摘要与纳入标准不兼容而被排除在外，27 篇文章因内容差异而被排除在外。在最终的筛选过程中，选择了 15 篇文章进行分析。从这 15 篇文章中可知，几种按蚊种存在有机氯（滴滴涕）、有机磷（马拉硫磷）和拟除虫菊酯类杀虫剂的抗性，死亡率低于 80%。: 本综述发现几种按蚊存在多种抗性，包括对拟除虫菊酯的抗性。由于拟除虫菊酯被认为在疟疾媒介控制中非常有效，因此关于其抗性的报告颇具挑战性。亚洲的几个国家正在按照全球抗药性管理计划实施针对疟疾媒介的杀虫剂抗药性管理（IRM）战略。
