Singh Balbir, Pai Paresh, Kumar Harish, George Sheeba, Mahapatra Sandeep, Garg Vineet, Gupta G N, Makineni Kiran, Ganeshwala Gaurav, Narkhede Pravin, Naqvi Syed M H, Gaurav Kumar, Hukkeri Mohammed Y K
Max Super Speciality Hospital, Saket, New Delhi, India.
Lilavati Hospital and Research Centre, Mumbai, Maharashtra, India.
Cardiol Ther. 2022 Mar;11(1):49-79. doi: 10.1007/s40119-022-00254-w. Epub 2022 Feb 8.
Non-vitamin K antagonist oral anticoagulants (NOACs) are a new class of anticoagulant drugs used in the prevention and treatment of venous thromboembolism (VTE) and atrial fibrillation (AF). Anticoagulation requires the integration of the correct type and dose of oral anticoagulants based on patient characteristic, and therefore therapy needs to be individualized for each patient. Growing scientific evidence from studies on NOACs has led to a better understanding of their benefits and safety. A large amount of available data creates a necessity for an adaptable practical document for the usage of NOACs in India. The current consensus, developed by experts from India, aims to give recommendations on various frequently raised clinical questions with regards to NOACs and its usage. This practical document provides a platform upon which future guidelines, policies, training, and education for the use of NOACs can be tailored.
非维生素K拮抗剂口服抗凝药(NOACs)是用于预防和治疗静脉血栓栓塞症(VTE)及心房颤动(AF)的一类新型抗凝药物。抗凝治疗需要根据患者特征选择正确类型和剂量的口服抗凝药,因此治疗需要针对每位患者进行个体化。关于NOACs的研究不断增加的科学证据,使人们对其益处和安全性有了更好的理解。大量现有数据使得有必要制定一份适用于印度NOACs使用情况的实用文件。由印度专家制定的当前共识旨在就有关NOACs及其使用的各种常见临床问题给出建议。这份实用文件提供了一个平台,据此可为未来使用NOACs的指南、政策、培训和教育进行量身定制。