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所有线粒体翻译产物都是在膜结合核糖体上合成的吗?

Are all mitochondrial translation products synthesized on membrane-bound ribosomes?

作者信息

Marzuki S, Hibbs A R

出版信息

Biochim Biophys Acta. 1986 Mar 26;866(2-3):120-4. doi: 10.1016/0167-4781(86)90108-9.

Abstract

The Arrhenius kinetics for the synthesis of var1, which is a hydrophilic protein of the mitochondrial ribosomes, have been compared to that of other mitochondrial translation products, which are hydrophobic subunits of the respiratory enzyme complexes. Our results indicate that, in the yeast Saccharomyces cerevisiae, the hydrophilic var1 protein is synthesized on membrane-associated mitochondrial ribosomes which cannot be distinguished from those responsible for the synthesis of the hydrophobic mitochondrial translation products.

摘要

已将线粒体核糖体的亲水性蛋白质var1合成的阿累尼乌斯动力学与呼吸酶复合物的疏水性亚基等其他线粒体翻译产物的动力学进行了比较。我们的结果表明,在酿酒酵母中,亲水性var1蛋白是在与膜相关的线粒体核糖体上合成的,这些核糖体与负责合成疏水性线粒体翻译产物的核糖体无法区分。

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