用于评估和管理人类过敏性疾病的临床实验室方法。

Clinical laboratory methods for the assessment and management of human allergic diseases.

作者信息

Hamilton R G, Adkinson N F

出版信息

Clin Lab Med. 1986 Mar;6(1):117-38.

Abstract

The biologic role and clinical relevance of IgE (reaginic) antibodies in immediate-hypersensitivity (allergic) reactions are reviewed, and methods useful in the laboratory diagnosis and management of human allergic diseases are discussed. Quantitative immunoassays for total and allergen-specific IgE antibodies are examined within the context of their use in diagnosis. The radioallergosorbent test inhibition assay and specific IgG antibody immunoassays are described as useful methods in the planning and monitoring of immunotherapy.

摘要

本文综述了IgE（反应素）抗体在速发型超敏反应（过敏反应）中的生物学作用及临床相关性，并讨论了在人类过敏性疾病实验室诊断和管理中有用的方法。在诊断用途的背景下，对总IgE抗体和过敏原特异性IgE抗体的定量免疫测定进行了研究。放射变应原吸附试验抑制测定和特异性IgG抗体免疫测定被描述为免疫治疗计划和监测中的有用方法。