University of Queensland-Gatton Campus, The University of Queensland, Gatton QLD 4343, Australia,
University of Queensland-Gatton Campus, The University of Queensland, Gatton QLD 4343, Australia.
J Avian Med Surg. 2022 Jan;35(4):464-474. doi: 10.1647/20-00023.
This case series describes polycystic kidney disease in 3 (2 male, 1 female) 2-month-old, juvenile rainbow lorikeets (). The lorikeets diagnosed with polycystic kidney disease were the progeny of full sibling parents that were being intentionally line bred for the purpose of establishing a rainbow lorikeet with the blue color mutation. Clinically the juvenile lorikeets were presented with clinical signs of lethargy, dehydration, regurgitation, anorexia, polyuria, and pelvic limb paresis. Multiple abnormalities were identified on the complete blood count and plasma biochemistry panel, including a normocytic normochromic nonregenerative anemia, hyperuricemia, hyperphosphatemia, hypercalcemia, and azotemia. Severe renal dysfunction was diagnosed in all birds on the basis of clinical presentation, physical examination, and complete blood count and plasma biochemistry results. Radiographically marked renomegaly was noted in one of the cases. Although intensive critical care and supportive therapy was provided, 1 lorikeet died, and the remaining 2 were euthanatized because of client financial constraints and a rapid deterioration of their clinical condition associated with severe renal dysfunction. Postmortem pathology results found that all birds had marked renomegaly, visceral gout, and polycystic kidney disease. Because of the age of the birds and the line breeding within this group of lorikeets, the disease was believed to be inherited. Polycystic kidney disease should be considered as a possible differential diagnosis in juvenile psittacine birds with a history of line breeding when presented with severe renal dysfunction. From the current case series, polycystic kidney disease appears to carry a grave prognosis in juvenile rainbow lorikeets.
本病例系列描述了 3 只（2 雄 1 雌）2 月龄的幼彩虹吸蜜鹦鹉（）多囊肾病。诊断为多囊肾病的吸蜜鹦鹉是同窝亲代父母的后代，这些亲代父母是为了培育出具有蓝色突变的彩虹吸蜜鹦鹉而有意近亲繁殖的。临床症状表现为幼鸟嗜睡、脱水、反流、厌食、多尿和后肢瘫痪。全血细胞计数和血浆生化小组发现多种异常，包括正细胞正色素非再生性贫血、高尿酸血症、高磷酸血症、高钙血症和氮血症。根据临床症状、体检、全血细胞计数和血浆生化结果，所有鸟类均被诊断为严重肾功能障碍。在一个病例中，发现明显的肾肿大。尽管提供了强化的重症监护和支持治疗，但有 1 只吸蜜鹦鹉死亡，其余 2 只因客户的经济限制和严重肾功能障碍相关的临床状况迅速恶化而被安乐死。尸检病理学结果发现所有鸟类均有明显的肾肿大、内脏痛风和多囊肾病。由于鸟类的年龄和该组吸蜜鹦鹉的近亲繁殖，该疾病被认为是遗传性的。当具有近亲繁殖史的幼年鹦鹉出现严重肾功能障碍时，应将多囊肾病作为可能的鉴别诊断。从目前的病例系列来看，多囊肾病似乎对幼年彩虹吸蜜鹦鹉预后严重。
