Godwin Kristen S, Mathai Mariam, Do Brian K
Medstar Georgetown/ Washington Hospital Center Department of Ophthalmology, 110 Irving St NW, Washington, D.C, 20010, USA.
The Retina Group of Washington, 8270 Willow Oaks Corporate Drive, 6th Floor, Fairfax, VA, 22031, USA.
Am J Ophthalmol Case Rep. 2022 Jan 31;25:101331. doi: 10.1016/j.ajoc.2022.101331. eCollection 2022 Mar.
Biologics have proven to be essential therapeutic agents in immune-mediated systemic diseases. Ophthalmologic adverse effects have been reported in the use of more traditional agents, such as TNF-α inhibitors, but there are limited data on ocular side effects associated with the newer generation of biologics.
In this report, we present a case of a suspected ustekinumab-associated recurrent sclerouveitis.
To the best of our knowledge, this is the first reported case of this type seen with ustekinumab injections. Our goal is to add to the existing literature in order to better understand the mechanism and management of this condition.
生物制剂已被证明是免疫介导的全身性疾病的重要治疗药物。在使用更传统的药物（如肿瘤坏死因子-α抑制剂）时已报告有眼科不良反应，但关于新一代生物制剂相关眼部副作用的数据有限。
在本报告中，我们介绍了一例疑似与优特克单抗相关的复发性巩膜葡萄膜炎病例。
据我们所知，这是首例报道的优特克单抗注射所致此类病例。我们的目标是补充现有文献，以便更好地了解这种情况的机制和管理。
