Jyväkorpi S K, Lindström M, Suominen M H, Kautiainen H, Salminen K, Niskanen R T, Pitkälä K H, Roitto H-M
University of Helsinki, Clinicum, Finland.
City of Helsinki Department of Social Services and Health Care, Geriatric Clinic, Helsinki Hospital, Helsinki, Finland.
Aging Clin Exp Res. 2022 Jun;34(6):1357-1363. doi: 10.1007/s40520-022-02077-0. Epub 2022 Feb 11.
Our aim was to explore the relationship between frailty, nutrition, body composition, and how gender modifies this relationship among long-term care facility residents. We further investigated how body composition correlates with health-related quality of life (HRQoL) in both genders. In all, 549 residents (> 65 years of age) were recruited from 17 long-term care facilities for this cross-sectional study. Demographic information, diagnoses, use of medications, and nutritional supplements were retrieved from medical records. Participants' frailty status, cognition, nutritional status, HRQoL, and body composition were determined. Energy, protein, and fat intakes were retrieved from 1- to 2-day food diaries. The final sample consisted of 300 residents (77% women, mean age 83 years). The majority of participants, 62% of women and 63% of men, were identified as frail. Frail participants in both genders showed lower body mass index (p = 0.0013), muscle mass (MM) (p < 0.001), poorer nutritional status (p = 0.0012), cognition (p = 0.0021), and lower HRQoL (p < 0.001) than did prefrail participants. Women had higher fat mass, whereas men exhibited higher MM. The HRQoL correlated with the MM in both women, r = 0.48 [95% CI 0.38, 0.57] and men r = 0.49 [95% CI 0.38, 0.58]. Interventions aimed at strengthening and retaining MM of long-term residents may also support their HRQoL.
我们的目的是探讨长期护理机构居民中衰弱、营养、身体成分之间的关系，以及性别如何改变这种关系。我们进一步研究了身体成分在男女两性中与健康相关生活质量（HRQoL）的相关性。总共从17家长期护理机构招募了549名居民（年龄>65岁）进行这项横断面研究。从医疗记录中获取人口统计学信息、诊断结果、药物使用情况和营养补充剂信息。确定参与者的衰弱状态、认知、营养状况、HRQoL和身体成分。从1至2天的饮食日记中获取能量、蛋白质和脂肪摄入量。最终样本包括300名居民（77%为女性，平均年龄83岁）。大多数参与者，62%的女性和63%的男性，被认定为衰弱。与非衰弱参与者相比，两性中的衰弱参与者均表现出较低的体重指数（p = 0.0013）、肌肉量（MM）（p < 0.001）、较差的营养状况（p = 0.0012）、认知（p = 0.0021）和较低的HRQoL（p < 0.001）。女性的脂肪量较高，而男性的MM较高。HRQoL在女性中与MM相关，r = 0.48 [95% CI 0.38, 0.57]，在男性中r = 0.49 [95% CI 0.38, 0.58]。旨在增强和维持长期居民MM的干预措施也可能有助于提高他们的HRQoL。
