Psychology Department, University of Montreal, Marie Victorin Building, 90 Vincent-D'Indy Avenue, Montreal, QC H2V 2S9, Canada.
Pôle en neuropsychologie et neuroscience cognitive et computationnelle (CerebrUM), University of Montreal, Marie Victorin Building, 90 Vincent-D'Indy Avenue, Montreal, QC H2V 2S9, Canada.
Cereb Cortex. 2022 Nov 21;32(23):5467-5477. doi: 10.1093/cercor/bhac027.
Neuronal repetition effect (repetition suppression and repetition enhancement) and change detection responses are fundamental brain responses that have implications in learning and cognitive development in infants and children. Studies have shown altered neuronal repetition and change detection responses in various clinical populations. However, the developmental course of these neuronal responses from infancy through childhood is still unknown. Using an electroencephalography oddball task, we investigate the developmental peculiarities of repetition effect and change detection responses in 43 children that we followed longitudinally from 3 months to 4 years of age. Analyses were conducted on theta (3-5 Hz), alpha (5-10 Hz), and beta (10-30 Hz) time-frequency windows. Results indicated that in the theta time-frequency window, in frontocentral and frontal regions of the brain, repetition and change detection responses followed a U-shaped pattern from 3 months to 4 years of age. Moreover, the change detection response was stronger in young infants compared to older children in frontocentral regions, regardless of the time-frequency window. Our findings add to the evidence of top-down modulation of perceptual systems in infants and children.
神经元重复效应（重复抑制和重复增强）和变化检测反应是基本的大脑反应，对婴儿和儿童的学习和认知发展有影响。研究表明，各种临床人群的神经元重复和变化检测反应发生了改变。然而，从婴儿期到儿童期这些神经元反应的发展过程尚不清楚。我们使用脑电图的Oddball 任务，对 43 名儿童进行了纵向研究，从 3 个月到 4 岁，我们跟踪了这些儿童的神经元重复效应和变化检测反应。分析在 theta（3-5Hz）、alpha（5-10Hz）和 beta（10-30Hz）时频窗口进行。结果表明，在 theta 时频窗口中，大脑额区和前区的重复和变化检测反应呈现出从 3 个月到 4 岁的 U 型模式。此外，在额区，无论时频窗口如何，幼儿的变化检测反应都比年长儿童更强。我们的发现为婴儿和儿童的感知系统的自上而下的调制提供了更多证据。
