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创伤性脑损伤和创伤后应激障碍的病理学与治疗综述。

A review of the pathology and treatment of TBI and PTSD.

作者信息

Monsour Molly, Ebedes Dominique, Borlongan Cesario V

机构信息

Center of Excellence for Aging and Brain Repair, University of South Florida Morsani College of Medicine, 12901 Bruce B Downs Blvd, Tampa, FL 33612, USA.

Center of Excellence for Aging and Brain Repair, University of South Florida Morsani College of Medicine, 12901 Bruce B Downs Blvd, Tampa, FL 33612, USA.

出版信息

Exp Neurol. 2022 May;351:114009. doi: 10.1016/j.expneurol.2022.114009. Epub 2022 Feb 9.

DOI:10.1016/j.expneurol.2022.114009
PMID:35150737
Abstract

This literature review focuses on the underlying pathophysiology of TBI and PTSD symptoms, while also examining the plethora of stem cell treatment options to ameliorate these neuronal and functional changes. As more veterans return suffering from TBI and/or PTSD, it is vital that researchers discover novel therapies to mitigate the detrimental symptoms of both diagnoses. A variety of stem cell treatments have been studied and offer hopeful options for TBI and PTSD recovery.

摘要

这篇文献综述聚焦于创伤性脑损伤(TBI)和创伤后应激障碍(PTSD)症状的潜在病理生理学,同时也研究了大量用于改善这些神经元和功能变化的干细胞治疗方案。随着越来越多的退伍军人带着创伤性脑损伤和/或创伤后应激障碍归来,研究人员发现新的疗法来减轻这两种病症的有害症状至关重要。已经对多种干细胞治疗方法进行了研究,它们为创伤性脑损伤和创伤后应激障碍的恢复提供了有希望的选择。

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