Donís Sergio Piñeiro, García Abel García, Vila Pilar Gándara, Carrión Andrés Blanco, Jornet Pía López, Peñaranda José M Suárez, Sayáns Mario Pérez
Department of Oral Surgery and Implantology, MedOralRes Group, Faculty of Medicine and Dentistry, University of Santiago de Compostela, Spain.
ORALRES Group, Health Research Institute of Santiago de Compostela (IDIS), Spain.
Natl J Maxillofac Surg. 2021 Sep-Dec;12(3):297-302. doi: 10.4103/njms.NJMS_120_20. Epub 2021 Dec 13.
Metastases from malignant tumors in the oral cavity are rare and comprise approximately 1% of all oral neoplasms, being more frequent in the jaws than in the soft tissues. The presentation of a gingival metastasis as the first manifestation of a primary tumor in the oral cavity is extremely rare. The objective of this review is to update the diagnosis and management of oral metastasis being the first clinical manifestation of the tumor and review all the cases published to date, providing a new original clinical case with very specific histopathological characteristics. We systematically reviewed the literature in order to find all the cases of primary lung tumors that appeared with a gingival metastasis as the first manifestation. The search process involved a total of 1916 articles. After reading the latter, 15 (one of them with two different cases) met the inclusion criteria. Of the 15 articles, 6 were rated as medium quality (40%) and 9 as high quality (60%). We present a lung adenocarcinoma that first manifested as a metastasis in the gum, simulating a benign lesion. The unusually high growth rate of this lesion should conduct to have other diagnostic possibilities, and histopathological confirmation is essential.
口腔恶性肿瘤的转移罕见，约占所有口腔肿瘤的1%，在颌骨中比在软组织中更常见。牙龈转移作为口腔原发性肿瘤的首发表现极为罕见。本综述的目的是更新作为肿瘤首发临床表现的口腔转移瘤的诊断和治疗，并回顾迄今为止发表的所有病例，提供一个具有非常特殊组织病理学特征的新的原始临床病例。我们系统地回顾了文献，以查找所有以牙龈转移为首发表现的原发性肺癌病例。检索过程共涉及1916篇文章。阅读这些文章后，有15篇（其中1篇包含两个不同病例）符合纳入标准。在这15篇文章中，6篇被评为中等质量（40%），9篇被评为高质量（60%）。我们报告一例肺腺癌，最初表现为牙龈转移，类似良性病变。该病变异常高的生长速度应促使考虑其他诊断可能性，组织病理学确诊至关重要。
