Nuyen Brian A, Tang Christopher G
Medical Student at the University of California, San Diego School of Medicine in La Jolla, CA.
Otolaryngologist and Head and Neck Surgeon at the San Francisco Medical Center in CA.
Perm J. 2016 Winter;20(1):71-3. doi: 10.7812/TPP/15-057.
Secondary oral cavity neoplasms are rare. We describe a case of an indurated, nonulcerating gingival lesion in a 59-year-old nonsmoking man with no family history of lung cancer. The lesion was the presenting symptom of metastatic lung adenocarcinoma. Reviewing the literature, we find that primary lung cancer among men is one of the most common cancers to metastasize to the oral cavity. Renal and cutaneous neoplasms are the next most common neoplasms to metastasize to the oral cavity. Furthermore, the gingiva, a tissue prone to inflammation, is noted to be a common site for secondary oral cavity neoplasms. This rare case highlights that metastases should influence the clinician's differential of oral mucosal lesions.
继发性口腔肿瘤较为罕见。我们描述了一例发生在一名59岁不吸烟男性身上的硬结性、非溃疡性牙龈病变,该男子无肺癌家族史。该病变是转移性肺腺癌的首发症状。回顾文献,我们发现男性原发性肺癌是最常转移至口腔的癌症之一。肾肿瘤和皮肤肿瘤是接下来最常转移至口腔的肿瘤。此外,牙龈是易于发生炎症的组织,被认为是继发性口腔肿瘤的常见部位。这个罕见病例突出表明,转移瘤应影响临床医生对口腔黏膜病变的鉴别诊断。