Honton Benjamin, Monsegu Jacques
Department of Interventional Cardiology, Clinique Pasteur Toulouse, France.
Department of Interventional Cardiology, Institut Cardio-Vasculaire, Groupe Hospitalier Mutualiste Grenoble, France.
Interv Cardiol. 2022 Jan 28;17:e02. doi: 10.15420/icr.2021.14. eCollection 2022 Jan.
Intravascular lithotripsy (IVL) is a novel approach to lesion preparation of severely calcified plaques in coronary and peripheral vessels. Lithotripsy is delivered by vaporising fluid to create an expanding bubble that generates sonic pressure waves that interact with arterial calcification. Available data indicate that IVL leads to increased vessel compliance before stent implantation with high efficacy and an excellent safety profile. Since it gained the CE mark in 2017, and with improved operator experience, the use of IVL has expanded into more complex clinical situations. This review focuses on the best practice for IVL use in the cath lab, based on 3 years of experience with the technology and the latest scientific data from the Disrupt CAD clinical trials.
血管内碎石术(IVL)是一种用于冠状动脉和外周血管严重钙化斑块病变预处理的新方法。通过汽化液体来产生碎石术,从而形成一个不断膨胀的气泡,该气泡会产生与动脉钙化相互作用的声压波。现有数据表明,在支架植入前,IVL可有效提高血管顺应性,且安全性极佳。自2017年获得CE标志以来,随着操作者经验的增加,IVL的应用已扩展到更复杂的临床情况。基于3年的技术经验以及“Disrupt CAD”临床试验的最新科学数据,本综述重点关注IVL在导管室中的最佳应用实践。