Lee Ji-Young, Oh Seok-Won, Ryu Han-Young, Seo Young-Seok
R & D Center, Wontech Co., Ltd., Daejeon 34028, Korea.
J Lasers Med Sci. 2021 Oct 3;12:e55. doi: 10.34172/jlms.2021.55. eCollection 2021.
Obesity is a global problem because it causes various complications. Methods for reducing fat for healthy life are being studied. In this study, we developed a minimally invasive and non-invasive lipolysis laser system for effective fat reduction. The laser had the wavelengths of 1980 nm and 2300 nm which have very good absorption of fat and water. We developed a minimally invasive laser system that breaks down fat by direct irradiation of fat tissue. This minimally invasive laser system uses a 808 nm diode laser and Nd:YVO to generate the 1064 nm wavelength, which is the pumping source of the nonlinear crystals. It is a mid-infrared lipolysis laser system having two wavelengths of 1980 nm and 2300 nm by controlling the temperature of nonlinear crystals. We also developed a non-invasive laser system that reduces fat with hyperthermia treatment by raising the temperature of adipocytes with a 1060 nm penetrating depth into the skin. In this non-invasive laser system, the In gallium arsenide (GaAs) diode laser is irradiated on the skin with an area of 4 × 8 cm through the hand-piece. The cooling system in the hand-piece protects the skin from burns. We studied the effectiveness and safety of each system through animal experiment. We studied the effects of lipolysis when these two systems were combined. This research uses new wavelengths (1980 nm, 2300 nm) to increase the fat reduction effect with low energy (1.3 W). After using the 1060 nm (1.1 W/cm) wavelength laser, when the 1980 nm and 2300 nm (1.3 W) laser were used, a lipolysis effect of about 35 % was obtained. We have developed a 1.3 W mid-infrared (1980 nm, 2300 nm) laser with good lipolysis effect with low power.
肥胖是一个全球性问题，因为它会引发各种并发症。人们正在研究通过减少脂肪来实现健康生活的方法。在本研究中，我们开发了一种用于有效减脂的微创和无创脂肪分解激光系统。该激光具有1980纳米和2300纳米的波长，对脂肪和水具有很好的吸收性。我们开发了一种通过直接照射脂肪组织来分解脂肪的微创激光系统。这种微创激光系统使用808纳米二极管激光器和Nd:YVO产生1064纳米波长，该波长是非线性晶体的泵浦源。通过控制非线性晶体的温度，它是一种具有1980纳米和2300纳米两个波长的中红外脂肪分解激光系统。我们还开发了一种无创激光系统，通过用穿透深度为1060纳米的激光提高脂肪细胞温度，利用热疗来减少脂肪。在这种无创激光系统中，砷化铟镓（GaAs）二极管激光器通过手持件照射在面积为4×8平方厘米的皮肤上。手持件中的冷却系统可保护皮肤免受灼伤。我们通过动物实验研究了每个系统的有效性和安全性。我们研究了这两种系统联合使用时的脂肪分解效果。本研究使用新波长（1980纳米、2300纳米）以低能量（1.3瓦）提高减脂效果。在使用1060纳米（1.1瓦/平方厘米）波长的激光后，当使用1980纳米和2300纳米（1.3瓦）的激光时，获得了约35%的脂肪分解效果。我们已经开发出一种具有良好脂肪分解效果且功率低的1.3瓦中红外（1980纳米、2300纳米）激光器。
