Díaz-Díaz Lymarie M, Rodríguez-Villafañe Andrea, García-Arrarás José E
Department of Biology, University of Puerto Rico, Río Piedras Campus, San Juan, Puerto Rico.
Front Cell Dev Biol. 2022 Jan 26;9:768783. doi: 10.3389/fcell.2021.768783. eCollection 2021.
The microbiota, the set of microorganisms associated with a particular environment or host, has acquired a prominent role in the study of many physiological and developmental processes. Among these, is the relationship between the microbiota and regenerative processes in various organisms. Here we introduce the concept of the microbiota and its involvement in regeneration-related cellular events. We then review the role of the microbiota in regenerative models that extend from the repair of tissue layers to the regeneration of complete organs or animals. We highlight the role of the microbiota in the digestive tract, since it accounts for a significant percentage of an animal microbiota, and at the same time provides an outstanding system to study microbiota effects on regeneration. Lastly, while this review serves to highlight echinoderms, primarily holothuroids, as models for regeneration studies, it also provides multiple examples of microbiota-related interactions in other processes in different organisms.
微生物群是与特定环境或宿主相关的一组微生物，在许多生理和发育过程的研究中发挥着重要作用。其中包括微生物群与各种生物体再生过程之间的关系。在此，我们介绍微生物群的概念及其在与再生相关的细胞事件中的作用。然后，我们回顾微生物群在从组织层修复到完整器官或动物再生的再生模型中的作用。我们强调微生物群在消化道中的作用，因为它在动物微生物群中占很大比例，同时提供了一个研究微生物群对再生影响的出色系统。最后，虽然本综述旨在突出棘皮动物，主要是海参，作为再生研究的模型，但它也提供了不同生物体其他过程中与微生物群相关相互作用的多个例子。
