Mashanov Vladimir S, Zueva Olga R, García-Arrarás José E
Department of Biology; University of Puerto Rico; San Juan, PR.
Mob Genet Elements. 2012 Sep 1;2(5):244-247. doi: 10.4161/mge.22644.
Research on the involvement of retroelements in developmental processes has been gaining momentum recently; however, most of the studies published so far have been focused on embryonic development. This commentary presents two recent papers, which document significant changes in transcriptional activity of retroelements in two different model systems, salamander limb regeneration and regeneration of radial organs in the sea cucumber . We hypothesize that transcriptional activity of the retrotransposons can be specifically controlled by the host and may play some hitherto unrecognized role in regeneration.
逆转录元件参与发育过程的研究近来势头渐盛；然而，迄今为止发表的大多数研究都集中在胚胎发育方面。本述评介绍了两篇近期论文，它们记录了逆转录元件在两种不同模型系统——蝾螈肢体再生和海参辐射器官再生——中转录活性的显著变化。我们推测，逆转录转座子的转录活性可能受到宿主的特异性调控，并可能在再生过程中发挥一些迄今尚未被认识到的作用。
