Duale Anoud, Singh Parul, Al Khodor Souhaila
Division of Maternal and Child Health, Department of Translational Medicine, Research Branch, Sidra Medicine, Doha, Qatar.
College of Health and Life Sciences, Hamad Bin Khalifa University, Ar-Rayyan, Qatar.
Front Nutr. 2022 Jan 26;8:800927. doi: 10.3389/fnut.2021.800927. eCollection 2021.
A mother is gifted with breast milk, the natural source of nutrition for her infant. In addition to the wealth of macro and micro-nutrients, human milk also contains many microorganisms, few of which originate from the mother, while others are acquired from the mouth of the infant and the surroundings. Among these microbes, the most commonly residing bacteria are and . These microorganisms initiate and help the development of the milk microbiota as well as the microbiota of the gastrointestinal tract in infants, and contribute to developing immune regulatory factors such as cytokines, growth factors, lactoferrin among others. These factors play an important role in reducing the risk of developing chronic diseases like type 2 diabetes, asthma and others later in life. In this review, we will summarize the known benefits of breastfeeding and highlight the role of the breast milk microbiota and its cross-talk with the immune system in breastfed babies during the early years of life.
母亲拥有母乳,这是婴儿天然的营养来源。除了丰富的宏量和微量营养素外,人乳还含有许多微生物,其中很少一部分源自母亲,而其他微生物则是从婴儿口腔和周围环境中获得的。在这些微生物中,最常见的常驻细菌是 和 。这些微生物启动并帮助婴儿乳汁微生物群以及胃肠道微生物群的发育,并有助于产生免疫调节因子,如细胞因子、生长因子、乳铁蛋白等。这些因素在降低日后患2型糖尿病、哮喘等慢性疾病的风险方面发挥着重要作用。在本综述中,我们将总结母乳喂养的已知益处,并强调母乳微生物群的作用及其在生命早期对母乳喂养婴儿免疫系统的相互作用。