Mechanosensitive Angiotensin II Receptor Signaling in Pressure-Induced Vasoconstriction.

作者信息

Chen Yen-Lin, Sonkusare Swapnil K

机构信息

Robert M. Berne Cardiovascular Research Center University of Virginia Charlottesville VA.

Department of Molecular Physiology and Biological Physics University of Virginia Charlottesville VA.

出版信息

J Am Heart Assoc. 2022 Feb 15;11(4):e024740. doi: 10.1161/JAHA.121.024740. Epub 2022 Feb 12.

DOI:10.1161/JAHA.121.024740

PMID:35156384

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9245830/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f438/9245830/ba7f2457a25e/JAH3-11-e024740-g001.jpg

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本文引用的文献

[1]

Myogenic Vasoconstriction Requires Canonical G Signaling of the Angiotensin II Type 1 Receptor.

J Am Heart Assoc. 2022-2-15

[2]

Endothelial TRPV4 channels and vasodilator reactivity.

Curr Top Membr. 2020

[3]

TRPV4 channel opening mediates pressure-induced pancreatitis initiated by Piezo1 activation.

J Clin Invest. 2020-5-1

[4]

Myogenic vasoconstriction requires G/G and LARG to maintain local and systemic vascular resistance.

Elife. 2019-9-24

[5]

PIP depletion promotes TRPV4 channel activity in mouse brain capillary endothelial cells.

Elife. 2018-8-7

[6]

Calcium Channels in Vascular Smooth Muscle.

Adv Pharmacol. 2017

[7]

Genetic ablation of CaV3.2 channels enhances the arterial myogenic response by modulating the RyR-BKCa axis.

Arterioscler Thromb Vasc Biol. 2015-8

[8]

A PLCγ1-dependent, force-sensitive signaling network in the myogenic constriction of cerebral arteries.

Sci Signal. 2014-5-27

[9]

Stretch-activation of angiotensin II type 1a receptors contributes to the myogenic response of mouse mesenteric and renal arteries.

Circ Res. 2014-5-16

[10]

Local control of TRPV4 channels by AKAP150-targeted PKC in arterial smooth muscle.

J Gen Physiol. 2014-5

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Mechanosensitive Angiotensin II Receptor Signaling in Pressure-Induced Vasoconstriction.

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