Free Dermatologist, Antalya, Turkey.
Cerrahpaşa Medical Faculty, Department of Dermatology and Venerology, İstanbul University-Cerrahpaşa, Fatih, Turkey.
J Cosmet Dermatol. 2022 May;21(5):1948-1952. doi: 10.1111/jocd.14845. Epub 2022 Feb 25.
Botulinum toxin-A (BoNT-A) has been increasingly used in the cosmetic dermatology daily routine. The treatment areas of BoNT-A are glabellar lines, forehead wrinkles, periorbital lines (crow's feet), eyebrow lifting, perioral lines, platysmal bands, masseter hypertrophy, and hyperhidrosis. The aim of this study was to reveal the epidemiologic characteristics of the patients treated with BoNT-A and the frequencies of treatment areas.
The patients were grouped into five categories: facial wrinkles, platysmal bands, masseter hypertrophy, axillary hyperhidrosis, and palmoplantar hyperhidrosis. Each patient received either onabotulinum toxin-A (diluted with 2 cc saline) or abobotulinum toxin-A (diluted with 3 cc saline) treatment. The patients' age, gender, and the total numbers of treatment received in each area were noted. SPSS version 21 was used for the statistical analysis.
A total of 1614 patients were included: 165 (6.5%) male and 1509 (93.5%) female. There is no difference between genders in terms of treatment area (p = 0.855). The number of treatment sessions is independent of the patients' gender (p = 0.703). The mean age of the patients was 46.6 years. There is a relationship between the patients' age and treatment area (sig 0.000). There is no relationship between the number of repetitive treatments and the patients' age (p=0.081). The number of repetitive treatments is dependent to the treatment area (p < 0.001).
Facial wrinkles, platysmal bands, and masseter hypertrophy are the most commonly treated areas. The treatment area is dependent on the age as platysmal bands are more commonly treated in older patients; however, no relationship between gender and treatment area was found. BoNT-A treatment for hyperhidrosis is not as commonly repeated as for that of cosmetic concerns.
肉毒杆菌毒素-A（BoNT-A）在日常美容皮肤科中应用越来越广泛。BoNT-A 的治疗区域包括眉间纹、额部皱纹、眶周纹（鱼尾纹）、提眉、口周纹、颈阔肌带、咬肌肥大和多汗症。本研究旨在揭示接受 BoNT-A 治疗的患者的流行病学特征和治疗区域的频率。
患者分为五类：面部皱纹、颈阔肌带、咬肌肥大、腋窝多汗症和手掌足底多汗症。每位患者均接受了肉毒毒素 A（用 2cc 生理盐水稀释）或 abobotulinumtoxin-A（用 3cc 生理盐水稀释）治疗。记录患者的年龄、性别以及每个区域接受的治疗总数。使用 SPSS 版本 21 进行统计分析。
共纳入 1614 例患者：男 165 例（6.5%），女 1509 例（93.5%）。不同性别在治疗区域方面无差异（p=0.855）。治疗次数与患者性别无关（p=0.703）。患者的平均年龄为 46.6 岁。患者年龄与治疗区域有关（sig 0.000）。重复治疗的次数与患者年龄无关（p=0.081）。重复治疗的次数取决于治疗区域（p<0.001）。
面部皱纹、颈阔肌带和咬肌肥大是最常治疗的区域。治疗区域取决于年龄，因为颈阔肌带在老年患者中更常见；然而，未发现性别与治疗区域之间存在关系。与美容相关的治疗相比，多汗症的 BoNT-A 治疗重复率并不高。
