Department of Oral and Maxillofacial Diagnostic Sciences, College of Dentistry, University of Florida, Gainesville, FL, USA.
Department of Pathology, Immunology and Laboratory Medicine, College of Medicine, University of Florida, 1600 SW Archer Rd, Gainesville, FL, 32010, USA.
Head Neck Pathol. 2022 Sep;16(3):918-927. doi: 10.1007/s12105-022-01427-8. Epub 2022 Feb 14.
Sinonasal leiomyosarcoma (LMS) is a rare and aggressive mesenchymal tumor with smooth muscle differentiation. The sinonasal tract is an unusual primary site for LMS, as scant smooth muscle exists in this location, with only 75 cases reported in the English literature including the case presented herein. Sinonasal LMS is considered an aggressive head and neck tumor with significant potential for recurrence and metastasis. Since recurrence is high and the potential for late metastasis exists, lifelong follow-up in these patients would be beneficial, especially among those with previous history of RB.
鼻腔鼻窦平滑肌肉瘤(LMS)是一种罕见且具有侵袭性的间叶组织肿瘤,具有平滑肌分化特征。鼻腔鼻窦是 LMS 少见的原发部位,因为此处平滑肌含量很少,包括本文报告的病例在内,英文文献中仅报道了 75 例。鼻腔鼻窦 LMS 被认为是一种侵袭性头颈部肿瘤,具有较高的复发和转移潜能。由于复发率高且存在远处转移的潜在风险,对这些患者进行终身随访将是有益的,特别是对于那些有 RB 病史的患者。