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Sinonasal cancer in the Italian national surveillance system: Epidemiology, occupation, and public health implications.意大利国家监测系统中的鼻腔鼻窦癌:流行病学、职业和公共卫生影响。
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World J Nucl Med. 2016 Sep;15(3):212-4. doi: 10.4103/1450-1147.172306.
3
Multifocal, recurrent sinonasal leiomyosarcoma: case report and review of literature.多灶性复发性鼻窦平滑肌肉瘤:病例报告及文献复习
Am J Otolaryngol. 2014 Mar-Apr;35(2):254-6. doi: 10.1016/j.amjoto.2013.10.011. Epub 2013 Nov 7.
4
Predictors of survival and recurrence in primary leiomyosarcoma.原发性平滑肌肉瘤的生存和复发预测因素。
Ann Surg Oncol. 2013 Jun;20(6):1851-7. doi: 10.1245/s10434-013-2876-y. Epub 2013 Jan 25.
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Prognostic factors in sinonasal sarcomas: analysis of the surveillance, epidemiology and end result database.鼻窦肉瘤的预后因素:监测、流行病学和最终结果数据库分析。
Laryngoscope. 2012 Oct;122(10):2137-42. doi: 10.1002/lary.23442. Epub 2012 Jul 9.
6
Leiomyosarcoma of the head and neck: a population-based analysis.头颈部平滑肌肉瘤:一项基于人群的分析。
Arch Otolaryngol Head Neck Surg. 2011 Sep;137(9):921-4. doi: 10.1001/archoto.2011.147.
7
Radiation-induced leiomyosarcoma of the oropharynx.放射性口咽平滑肌肉瘤
Diagn Pathol. 2006 Aug 22;1:22. doi: 10.1186/1746-1596-1-22.
8
Leiomyosarcoma of the nasopharynx.鼻咽平滑肌肉瘤
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9
Leiomyosarcoma of the head and neck: a clinicopathological study.头颈部平滑肌肉瘤:一项临床病理研究。
Histopathology. 2002 Jun;40(6):518-25. doi: 10.1046/j.1365-2559.2002.01412.x.
10
Radiation induced sarcoma of the head and neck.辐射诱发的头颈部肉瘤
Head Neck. 1999 Jul;21(4):346-54. doi: 10.1002/(sici)1097-0347(199907)21:4<346::aid-hed9>3.0.co;2-b.

平滑肌肉瘤:一种罕见的鼻窦恶性肿瘤。

Leiomyosarcoma: a rare sinonasal malignancy.

作者信息

Kwok Matthew Ming Kei, Lee Stewart, Hosking Patrick

机构信息

Department of ENT, Eastern Health, Box Hill, Victoria, Australia.

Department of Pathology, Eastern Health, Box Hill, Victoria, Australia.

出版信息

BMJ Case Rep. 2018 Mar 27;2018:bcr-2017-224110. doi: 10.1136/bcr-2017-224110.

DOI:10.1136/bcr-2017-224110
PMID:29588301
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5878274/
Abstract

Leiomyosarcomas (LMS) are rare sinonasal malignant tumours with 20 cases of nasal LMS previously reported in the literature. An 81-year-old man presented with an incidental left nasal lesion associated with left nasal obstruction and occasional left-sided blood-stained rhinorrhoea. Nasendoscopic examination showed green coloured polyps filling the left nasal cavity with biopsies showing LMS. CT imaging did not show any bony erosion. No metastases were found on positron emission tomography imaging. The patient underwent endoscopic resection and all surgical margins were clear of disease. The patient was declined postoperative radiotherapy, and serial follow-up has not shown any recurrence to date. Nasal LMS are rare sinonasal smooth muscle tumours and symptoms and radiological findings are often non-specific. Therefore, diagnosis is made on histopathological and immunohistochemical analysis. Due to their invasive nature, the treatment of choice is complete surgical resection, with adjuvant therapy reserved for patients with locally advanced or metastatic disease.

摘要

平滑肌肉瘤(LMS)是一种罕见的鼻窦恶性肿瘤,此前文献中报道过20例鼻腔LMS。一名81岁男性因偶然发现左侧鼻腔病变就诊,伴有左侧鼻塞和偶尔的左侧血性鼻漏。鼻内镜检查显示绿色息肉充满左侧鼻腔,活检显示为LMS。CT成像未显示任何骨质侵蚀。正电子发射断层显像未发现转移。患者接受了内镜下切除术,所有手术切缘均无肿瘤残留。患者拒绝术后放疗,至今系列随访未显示任何复发迹象。鼻腔LMS是罕见的鼻窦平滑肌肿瘤,症状和影像学表现通常不具有特异性。因此,诊断依靠组织病理学和免疫组织化学分析。由于其具有侵袭性,治疗的首选方法是完整的手术切除,辅助治疗适用于局部晚期或转移性疾病患者。