Park Hye-Jin, Koo Soo Kweon, Choi Kyung-Un, Cho Kyu-Sup
Department of Otorhinolaryngology-Head and Neck Surgery, Pusan National University Hospital, Pusan National University School of Medicine, Busan, Republic of Korea.
Department of Otorhinolaryngology-Head and Neck Surgery, Busan Saint Mary's Hospital, Busan, Republic of Korea.
J Rhinol. 2025 Jul;32(2):108-112. doi: 10.18787/jr.2025.00028. Epub 2025 Jul 22.
Leiomyosarcoma (LMS) is a malignant tumor of smooth muscle origin that is most frequently found in the uterus and gastrointestinal tract. LMS involving the head and neck is rare, accounting for only 2.3% of all cases. In this region, LMS tends to be more aggressive and is associated with a poorer prognosis compared to its gastrointestinal counterparts. Furthermore, LMS of the nasal cavity and paranasal sinuses is extremely rare. Here, we present a case of malignant transformation of a leiomyoma originating from the inferior turbinate, which was successfully treated with endoscopic tumor resection followed by postoperative radiotherapy.
平滑肌肉瘤（LMS）是一种起源于平滑肌的恶性肿瘤，最常见于子宫和胃肠道。累及头颈部的LMS较为罕见，仅占所有病例的2.3%。在该区域，与胃肠道的LMS相比，头颈部LMS往往更具侵袭性，预后较差。此外，鼻腔和鼻窦的LMS极其罕见。在此，我们报告一例起源于下鼻甲的平滑肌瘤恶变病例，该病例通过内镜肿瘤切除及术后放疗成功治愈。
