Lippert B M, Godbersen G S, Lüttges J, Werner J A
Department of Otorhinolaryngology, Head and Neck Surgery, University of Kiel, Germany.
ORL J Otorhinolaryngol Relat Spec. 1996 Mar-Apr;58(2):115-20. doi: 10.1159/000276810.
Leiomyosarcoma (LMS) accounts for approximately 7% of all soft tissue sarcomas and occurs most frequently in the gastrointestinal tract and uterus. LMS of the nasal cavity and paranasal sinuses are rare and only about 40 cases of LMS of the nose and paranasal sinuses have been reported in the literature. A further case of LMS of the right turbinate is presented, treated twice by surgery. To date, the patient has been free of disease for more than 48 months. The symptoms, pathology, treatment and prognosis, and origin of this tumor are discussed. Initially, LMS should be treated by extensive surgical excision, but long-term follow-up is essential due to the high rate of local recurrence. Radiotherapy and chemotherapy are insufficient therapeutic approaches. Frequency of recurrence and prognosis depend on the tumor site. The prognosis of LMS of the nasal cavity is better than LMS of the paranasal sinuses.
平滑肌肉瘤（LMS）约占所有软组织肉瘤的7%，最常发生于胃肠道和子宫。鼻腔和鼻窦的LMS较为罕见，文献中仅报道了约40例鼻腔和鼻窦LMS病例。本文介绍了另一例右侧鼻甲LMS病例，该患者接受了两次手术治疗。迄今为止，患者已无病生存超过48个月。本文讨论了该肿瘤的症状、病理、治疗、预后及起源。LMS初始治疗应采用广泛手术切除，但由于局部复发率高，长期随访至关重要。放疗和化疗的治疗效果欠佳。复发频率和预后取决于肿瘤部位。鼻腔LMS的预后优于鼻窦LMS。
