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睡眠障碍性呼吸症状在青少年镰状细胞病患者神经认知功能中的作用。

The Role of Sleep-Disordered Breathing Symptoms in Neurocognitive Function Among Youth With Sickle Cell Disease.

机构信息

Department of Clinical & Health Psychology, University of Florida, Gainesville, Florida, USA.

Division of Pediatric Hematology and Oncology, College of Medicine, University of Florida, Gainesville, Florida, USA.

出版信息

Dev Neuropsychol. 2022 Mar-Apr;47(2):93-104. doi: 10.1080/87565641.2022.2038601. Epub 2022 Feb 14.

DOI:10.1080/87565641.2022.2038601
PMID:35157528
Abstract

OBJECTIVE

To examine associations between sleep-disordered breathing (SDB) and executive/attentional function in pediatric sickle cell disease (SCD).

METHODS

Sixty youth with SCD ages 8-18 years and caregivers completed the Pediatric Sleep Questionnaire (PSQ), Delis Kaplan Executive Function System Trail Making Test (DKEFS TMT), Psychomotor Vigilance Test (PVT), and the Behavior Rating Inventory Of Executive Function, Second Edition (BRIEF-2) Parent Report.

RESULTS

The PSQ significantly predicted the BRIEF-2 Parent Report, (1, 58) = 44.64, < .001, R = 0.44, f = 0.77.

CONCLUSIONS

Sleep-disordered breathing symptoms may predict informant-rated executive dysfunction in pediatric SCD, but not performance-based executive function.

摘要

目的

研究儿童镰状细胞病(SCD)中睡眠呼吸障碍(SDB)与执行/注意力功能之间的关系。

方法

60 名年龄在 8 至 18 岁的 SCD 青少年及其照顾者完成了儿科睡眠问卷(PSQ)、德里斯科尔·卡普兰执行功能系统连线测试(DKEFS TMT)、精神运动警觉测试(PVT)和行为评定量表第二版执行功能(BRIEF-2)父母报告。

结果

PSQ 显著预测 BRIEF-2 父母报告,(1,58)=44.64,<0.001,R=0.44,f=0.77。

结论

睡眠呼吸障碍症状可能预测儿童 SCD 中信息提供者评定的执行功能障碍,但不能预测基于表现的执行功能。

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