Department of Gastroenterology, Pak Emirates Military Hospital Rawalpindi, Pakistan.
Department of Gastroenterology, Pak Emirates Military Hospital, Rawalpindi, Pakistan.
J Pak Med Assoc. 2021 Jan;71(1(B)):376-378. doi: 10.47391/JPMA.1340.
Hepatitis-associated aplastic anaemia (HAAA) is an uncommon variant of aplastic anaemia which may present as acute or chronic, mild and transient or fulminant disease. The development of aplastic anaemia is usually fatal if not treated in time, with mortality rate being as high as 85%. A high index of clinical suspicion is required for the diagnosis and exclusion of acquired forms of aplastic anaemia. Here we present a case of a 28-year-old male who presented with sero-negative hepatitis and rapidly progressive bone marrow failure who was given a trial of Granulocyte Colony Stimulating Factor followed by a successful allogenic bone marrow transplant.
肝炎相关性再生障碍性贫血（HAAA）是再生障碍性贫血的一种罕见类型，可表现为急性或慢性、轻度和一过性或暴发性疾病。再生障碍性贫血的发展如果不及时治疗通常是致命的，死亡率高达 85%。为了诊断和排除获得性再生障碍性贫血，需要高度的临床怀疑指数。在这里，我们报告了一例 28 岁男性，他表现为血清阴性肝炎和迅速进展的骨髓衰竭，给予粒细胞集落刺激因子治疗后，进行了成功的同种异体骨髓移植。
