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[保留的犬胰腺的胰岛素和胰高血糖素分泌]

[Insulin and glucagon secretion of the preserved dog pancreas].

作者信息

Panzig E, Besch W, Beckert R, Rosenbaum K D, Kiene S, Jilg S, Rose H J

出版信息

Z Exp Chir Transplant Kunstliche Organe. 1986;19(1):3-8.

PMID:3515783
Abstract

Well defined results can be obtained quickly by in vitro test concerning the preservation effect of the preserved dog's pancreas. Clinical and chemical parameters were received during the hypothermic perfusion respectively during the refrigerant storage. The in vitro function tests were carried out after the preservation by insulin and glucagon stimulation. The results showed that the A and B cells of the dog's pancreas are completely able to function after a preservation of 24 hours. Thereby a strong formation of edemas by releasing high enzyme activities is caused during the mechanical perfusion of the organs. The simple refrigerant storage of the pancreata therefore, is the more suitable preservation form for organ transplantations.

摘要

通过体外试验可以快速获得关于保存犬胰腺的保存效果的确切结果。在低温灌注期间以及在冷藏保存期间分别获取临床和化学参数。在保存后通过胰岛素和胰高血糖素刺激进行体外功能测试。结果表明,犬胰腺的A细胞和B细胞在保存24小时后完全能够发挥功能。因此,在器官的机械灌注过程中,由于释放高酶活性而导致强烈的水肿形成。因此,胰腺的简单冷藏保存是器官移植更合适的保存形式。

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1
[Insulin and glucagon secretion of the preserved dog pancreas].[保留的犬胰腺的胰岛素和胰高血糖素分泌]
Z Exp Chir Transplant Kunstliche Organe. 1986;19(1):3-8.
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